Results 111 to 120 of about 52,285 (258)

The first detection of a serotype O foot-and-mouth disease virus in Namibia. [PDF]

Transbound Emerg Dis, 2022
Banda F, Shilongo A, Hikufe EH, Khaiseb S, Kabajani J, Shikongo B, Set P, Kapapero JK, Shoombe KK, Zaire G, Kabilika S, Quan M, Fana EM, Mokopasetso M, Hyera JMK, Wadsworth J, Knowles NJ, Nardo AD, King DP.   +18 more
europepmc   +1 more source

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

Biotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing, Tomoki Igi, Daniel Strauss   +2 more
wiley   +1 more source

Determination of baseline Widal titre in healthy individuals in Karbala city, South of Iraq

Journal of Contemporary Medical Sciences, 2015
Objective To determine the cutoff of antibodies directed against Salmonella enterica subspecies enterica serotype typhi, paratyphi A, and paratyphi B in normal population in Karbala city, south Iraq.
Suhad Hadi Mohammed
doaj  

Thermostable negative-marker foot-and-mouth disease virus serotype O induces protective immunity in guinea pigs. [PDF]

Appl Microbiol Biotechnol, 2023
Ranjitha HB, Dhanesh VV, Hosamani M, Sreenivasa BP, Jabeen U, Biswal JK, Saravanan P, Sanyal A, Bhanuprakash V, Basagoudanavar SH.   +9 more
europepmc   +1 more source

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

Biotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera, Ivan Gajic, Praveen Kusumanchi, Angela Andaluz, Gabrielle Dela Pena, Clifford A. Froelich, Elizabeth Higgins, Jennifer Johnston, Seyed Pouria Motevalian   +8 more
wiley   +1 more source

Emergence of a novel sublineage, MYMBD21 under SA-2018 lineage of Foot-and-Mouth Disease Virus serotype O in Bangladesh. [PDF]

Sci Rep, 2023
Hossain KA, Anjume H, Alam KMM, Yeamin A, Akter S, Hossain MA, Sultana M.   +6 more
europepmc   +1 more source

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

Clinical Pharmacology &Therapeutics, EarlyView.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts, Xavier Woot de Trixhe, Martine Neyens, Thomas N. Kakuda, Liesbeth Van Wesenbeeck, Annemie Buelens, Freya Rasschaert, Anna Durbin, Oliver Ackaert   +8 more
wiley   +1 more source

Efficacy of a Novel Multiepitope Vaccine Candidate against Foot-and-Mouth Disease Virus Serotype O and A. [PDF]

Vaccines (Basel), 2022
Chathuranga WAG, Hewawaduge C, Nethmini NAN, Kim TH, Kim JH, Ahn YH, Yoon IJ, Yoo SS, Park JH, Lee JS.   +9 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Production and characterization of monoclonal antibodies against foot-and-mouth disease virus serotype O and development of a sandwich ELISA for virus antigen detection. [PDF]

Vet Res Commun, 2023
Mallick S, Singh RP, Biswal JK, Mohapatra JK, Rout M, Samanta R, Khulape SA, Ranjan R.   +7 more
europepmc   +1 more source