Results 141 to 150 of about 54,993 (303)

Epizootiological study of foot and mouth disease in the Sudan: the situation after two decades

, 2010
Radi pružanja informacija o sadašnjem stanju slinavke i šapa u Sudanu provedena su serološka istraživanja te je prikazana njezina pojavnost. Svježe prikupljeni podatci o pojavi slinavke i šapa u Sudanu pokazali su da ona predstavlja veliku prepreku ...
Habiela, Mohammed, Ali, Yahia H., Alamin, Mohammed A. G., Yahia H. Ali, Yazeed A. Raouf, Mohammed Habiela, Mohammed A. G. Alamin, Raouf, Yazeed A.   +7 more
core  

Five‐Year Outcomes With Delandistrogene Moxeparvovec in Patients With Duchenne Muscular Dystrophy: A Phase 1/2a Study

Muscle &Nerve, EarlyView.
ABSTRACT Aims We report 5‐year results from a phase 1/2a study of delandistrogene moxeparvovec, a recombinant adeno‐associated virus serotype rh74 vector‐based gene therapy for Duchenne muscular dystrophy (DMD), with post hoc analyses contextualizing functional outcomes. Methods Four ambulatory patients with DMD (≥ 4–< 8 years at enrollment) entered an
Jerry R. Mendell, Zarife Sahenk, Linda P. Lowes, Megan A. Iammarino, Lindsay N. Alfano, Craig M. McDonald, James E. Signorovitch, Jim Jin, Jing Li, Stefanie Mason, Louise R. Rodino‐Klapac   +10 more
wiley   +1 more source

The Immunogenicity of a Foot-and-Mouth Disease Virus Serotype O Vaccine in Commercial and Subsistence Cattle Herds in Zambia. [PDF]

Vaccines (Basel), 2023
Banda F, Ludi AB, Wilsden G, Browning C, Kangwa HL, Mooya L, Ngoma M, Muuka GM, Mundia C, Fandamu P, Paton DJ, King DP, Quan M.   +12 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Botulinum toxin use in patients with neurological disorders: A U.S.‐based claims database analysis

PM&R, EarlyView.
Abstract Background and Objective Real‐world evidence describing long‐term persistency with botulinum toxin (BoNT) therapy is limited. We assessed treatment patterns and persistency with BoNT in clinical practice over 2 years. Design Retrospective, longitudinal, claims database analysis. Setting Medical claims data from the Merative MarketScan database
David M. Simpson, Jonathan Bouchard, Simon Page, Seth Goldfarb, Atul T. Patel   +4 more
wiley   +1 more source

Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu, Peng Hu, Zizhong Yang, Zhenghui Jin, Xiaoyu Zhu, Tao Wang, Jihong Liu, Kai Cui   +7 more
wiley   +1 more source

Amino acid residues in the tail fiber differentiate the host specificity of Cronobacter sakazakii bacteriophage

Journal of Virology
Cronobacter sakazakii is a Gram-negative pathogen that causes severe infections such as neonatal meningitis and sepsis. Bacteriophages (phages) rely on tail fibers for host recognition and infection, but the mechanisms of how phages recognize their ...
Eunshin Cho, Jinshil Kim, Nam-Chul Ha, Sangryeol Ryu   +3 more
doaj   +1 more source

Molecular evolution, diversity, and adaptation of foot-and-mouth disease virus serotype O in Asia. [PDF]

Front Microbiol, 2023
Li F, Li Y, Ma J, Wu R, Zou X, Liu Y, Zhao Q, Zhu Y.   +7 more
europepmc   +1 more source

Titration of anti-FMDV serotype O antibodies induced following infection with rescued serotype O FMDV.

, 2013
Values are reciprocals of highest serum dilutions yielding positive results in the blocking ELISA on the indicated day post inoculation (dpi). A (-) indicates samples which were scored negative in the spot test (see Figure 5B) and N.D.
Graham J. Belsham (116715), Anette Bøtner (72594), Kirsten Tjørnehøj (356864), Syed M. Jamal (356863)   +3 more
core   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source