Results 141 to 150 of about 52,285 (258)

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

φYeO3-12 phage tail fiber Gp17 as a promising high specific tool for recognition of Yersinia enterocolitica pathogenic serotype O:3. [PDF]

AMB Express, 2022
Filik K, Szermer-Olearnik B, Niedziółka-Jönson J, Roźniecka E, Ciekot J, Pyra A, Matyjaszczyk I, Skurnik M, Brzozowska E.   +8 more
europepmc   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity. [PDF]

J Virol, 2021
Dong H, Lu Y, Zhang Y, Mu S, Wang N, Du P, Zhi X, Wen X, Wang X, Sun S, Zhang Y, Guo H.   +11 more
europepmc   +1 more source

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss, Debra J. Ehrlich, Codrin Lungu, Joseph Y. Choi, Gretchen Scott, Irene Dustin, Dima A. Hammoud, Peter Herscovitch, Russell R. Lonser, Kareem A. Zaghloul, Krystof Bankiewicz   +10 more
wiley   +1 more source

A meta-analysis on the effectiveness of serotype O foot-and-mouth disease vaccines. [PDF]

Sci Rep
Jiao J, Yang H, Liang Z, Pan Y, Yang J, Zhang W, Wu P.   +6 more
europepmc   +1 more source

The High Immunity Induced by the Virus-Like Particles of Foot-and-Mouth Disease Virus Serotype O. [PDF]

Front Vet Sci, 2021
Xiao Y, Zhang S, Yan H, Geng X, Wang Y, Xu X, Wang M, Zhang H, Huang B, Pang W, Yang M, Tian K.   +11 more
europepmc   +1 more source

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

Movement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source

VP1 region-based molecular characterization of foot-and-mouth disease virus serotype O from clinical cases in Haryana, India. [PDF]

BMC Vet Res
Dalal P, Dahiya S, Lather A, Sheoran D, Sangwan P, Rani N, Pannu A, Kumar P, Kumar P, Subramaniam S, Singh RP.   +10 more
europepmc   +1 more source

Yersinia pseudotuberculosis serotype O:1 infection in a captive Seba's short tailed-fruit bat (Carollia perspicillata) colony in Switzerland. [PDF]

BMC Vet Res, 2021
Hahn K, Veiga IB, Schediwy M, Wiederkehr D, Meniri M, Schneeberger M, den Broek PR, Gurtner C, Fasel NJ, Kittl S, Fredriksson-Ahomaa M, Schmitt S, Stokar-Regenscheit N.   +12 more
europepmc   +1 more source