Results 21 to 30 of about 8,409 (168)

Streptococcus pneumoniae carriage, antimicrobial resistance, and serotype distribution in children and adults from Paraguay in the post-vaccinal era

Frontiers in Public Health
IntroductionInfections due to Streptococcus pneumoniae, including pneumonia and meningitis, are a leading cause of morbidity and mortality, especially in low-and lower middle-income countries (LMICs) worldwide.
Graciela Russomando, Graciela Russomando, Norma Fariña, Selilah Amour, Selilah Amour, Lorena Grau, Rosa Guillen, Sonia Abente, Monserrat Aldama, Ingrid Hahn, Hector Castro, Mélina Messaoudi, Zunilda Sanchez, Valentina Picot, Florence Komurian-Pradel, Milen Milenkov   +15 more
doaj   +1 more source

Characterization of Uropathogenic Pseudomonas aeruginosa: Serotypes, Resistance Phenotypes, and Virulence Genotypes

Journal of Pure and Applied Microbiology, 2022
Pseudomonas aeruginosa is a major cause of urinary tract infections. This organism has extended resistance to antimicrobials along with multiple virulence factors, making it difficult to treat.
Rehab Mohammed Elbargisy
doaj   +1 more source

Molecular and biological characterization of Streptococcus pneumoniae isolates from patients with pneumococcal meningitis

Журнал микробиологии, эпидемиологии и иммунобиологии
The aim of the study is to provide key characteristics of Streptococcus pneumoniae isolates circulating in Russia in 2015–2020 and isolated from pneumococcal meningitis patients based on high-throughput sequencing data, including global pneumococcal ...
Aida N. Chagaryan, Natali V. Ivanchik, Alexey Yu. Kuzmenkov, Roman S. Kozlov, Irina I. Gaponova, Konstantin O. Mironov   +5 more
doaj   +1 more source

Approaches to vaccination of adults against pneumococcal disease in different countries of the world

Журнал инфектологии
Various pneumococcal vaccines are available worldwide, differing in the range of serotypes coverage and type of vaccine, which determine different mechanisms of action and postvaccinal immunity. Vaccination  against  pneumococcal infection is recommended
A. S. Korovkin, Yu. I. Obukhov, E. N. Syatchikhina   +2 more
doaj   +1 more source

Emergence of Multi-Drug Resistance and Its Association With Uncommon Serotypes of Streptococcus agalactiae Isolated From Non-neonatal Patients in Thailand

Frontiers in Microbiology, 2021
Group B streptococcus (GBS) or Streptococcus agalactiae is an opportunistic pathogen that causes serious illness in newborns, pregnant women, and adults.
Orawan Tulyaprawat, Sujiraphong Pharkjaksu, Raj Kumar Shrestha, Popchai Ngamskulrungroj   +3 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Salmonella enterica serotypes causing infection in Kuwait during 2018–2021, determined by multi-locus sequence typing or whole genome sequencing

Microbiology Spectrum
Salmonellosis due to non-typhoidal Salmonellae (NTS) is a zoonotic infection that has epidemiological uniqueness in different settings. The current study aimed to determine the serotypes and the genetic diversity of human Salmonella enterica isolates ...
Amani H. Al Fadhli, Wafaa Y. Jamal, Fatema Bibi Khodakhast, Glen P. Carter, Dieter Bulach, M. John Albert   +5 more
doaj   +1 more source

Current State of the Streptococcus pneumoniae Capsular Typing Problem

Антибиотики и Химиотерапия, 2022
Diseases caused by Streptococcus pneumoniae are a serious medical and social problem for healthcare systems of all leading countries around the globe.
Yu. A. Zakharova, V. G. Akimkin, E. V. Nikitina, I. A. Ivashchenko, E. V. Bolgarova, E. V. Aleksandrova, S. M. Skripkovskaya   +6 more
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source