Results 61 to 70 of about 115,869 (313)

A multicentre study of Shigella diarrhoea in six Asian countries: disease burden, clinical manifestations, and microbiology. [PDF]

, 2006
BACKGROUND: The burden of shigellosis is greatest in resource-poor countries. Although this diarrheal disease has been thought to cause considerable morbidity and mortality in excess of 1,000,000 deaths globally per year, little recent data are available
Talukder Kaisar, Zulfiqar A Bhutta, Mohammad Ali, Seidlein, Lorenz von, Thiem, Vu Dinh, Deen Jacqueline L, Lee Hyejon, Deen, Jacqueline L, Kotloff, Karen, Nair G. B, G B Nair, Sethabutr Ornthipa, Lorenz von Seidlein, Hossain, Anowar, Talukder, Kaisar, Do Gia Canh, Canh Do Gia, Xuanyi Wang, Mason Carl, Ali, Mohammad, Ali Mohammad, Kim Deok Ryun, Magdarina D Agtini, von Seidlein Lorenz, Sethabutr, Ornthipa, von Seidlein, Lorenz, Karen Kotloff, Wanpen Chaicumpa, Agtini Magdarina D, Agtini, Magdarina D, Bhutta Zulfiqar A, Thiem Vu Dinh, Wang XuanYi, Vu Dinh Thiem, John Clemens, Hossain Anowar, Wang, Xuanyi, Nair, GB, Deok Ryun Kim, Ornthipa Sethabutr, Kaisar Talukder, Lee, Hyejon, Clemens, John, Jacqueline L Deen, Canh, Do Gia, Carl Mason, Mason, Carl, Chaicumpa Wanpen, Bhutta, Zulfiqar A, Clemens John, Agtini, Magdarina D., Bhutta, Zulfiqar A., Kim, Deok Ryun, Nair, G. B., Chaicumpa, Wanpen, Hyejon Lee, Kotloff Karen, Anowar Hossain, Deen, Jacqueline L.   +58 more
core   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Characterization of Listeria monocytogenes Originating from the Spanish Meat-Processing Chain

Foods, 2019
Using agglutination techniques, 118 Listeria monocytogenes isolates from red meat and poultry were serotyped. Strains were ascribed to the serotypes 4b/4e (44.1% of the strains), 1/2 (a, b or c; 28.0%), 4c (6.8%), 4d/4e (5.9%) and 3 (a, b or c; 2.5 ...
Rosa Capita, Amanda Felices-Mercado, Camino García-Fernández, Carlos Alonso-Calleja   +3 more
doaj   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Relatedness of Streptococcus suis isolates of various serotypes and clinical backgrounds as evaluated by macrorestriction analysis and expression of potential virulence traits

, 2001
We evaluated the genetic diversity of Streptococcus suis isolates of different serotypes by macrorestriction analysis and elucidated possible relationships between the genetic background, expression of potential virulence traits, and source of isolation.
Smith, H.E., Henk J. Wisselink, Allgaier, A., Wisselink, H.J., Valentin-Weigand, P., Achim Allgaier, Peter Valentin-Weigand, Goethe, R., Hilde E. Smith, Ralph Goethe   +9 more
core   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Antigenic and biochemical characterization of bovine rotavirus V1005, a new member of rotavirus serotype 10 [PDF]

, 1990
Bovine rotavirus (BRV) V1005 is serologically distinct from rotavirus serotypes 1, 2, 3, 4, 5, 6, 8 and 9. BRV V1005 showed cross-reactions with BRV B223, the American prototype of serotype 10 rotavirus, and with BRV E4049, a British serotype 10 isolate.
Bruttin, Anne, Fitzgerald, Tracey, Eichhorn, Werner, Snodgrass, David, Büssow, Harald, Gerhards, Roswitha   +5 more
core  

Chromosome sizes and phylogenetic relationships between serotypes of Actinobacillus pleuropneumoniae [PDF]

, 1998
The genome size of Actinobacillus pleuropneumoniae was determined by pulsed field gel electrophoresis of AscI and ApaI digested chromosomal DNA. The genome size of the type strain 4074T (serotype 1) was determined to be 2404±40 kb.
Harel, Josée, Kobisch, Marylène, Frey, Joachim, Chevallier, Bruno, Gottschalk, Marcelo, Dugourd, Dominique, Tarasiuk, Kazimirez   +6 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source