Results 71 to 80 of about 115,869 (313)

Monitoring the introduction of pneumococcal conjugate vaccines into West Africa: design and implementation of a population-based surveillance system. [PDF]

, 2012
Routine use of pneumococcal conjugate vaccines (PCVs) in developing countries is expected to lead to a significant reduction in childhood deaths. However, PCVs have been associated with replacement disease with non-vaccine serotypes.
Greenwood, Brian M, Wattiaux Andre, Stephen R C Howie, Effua Usuf, Sambou Sana, Plumb Ian D., Uchendu, Uchendu, Wattiaux, Andre, Maria Deloria Knoll, Howie Stephen R. C., Saha, Debasish, Ian D Plumb, Philip C Hill, Howie, Stephen RC, Ikumapayi Usman N., Mackenzie Grant A., Lee Ellen, Jasseh, Momodou, Greenwood Brian M., Sana Sambou, Debasish Saha, Akinsola, Bolanle, Ellen Lee, Hill, Philip C, Brian M Greenwood, Jasseh Momodou, Adegbola, Richard A, Plumb, Ian D, Hill Philip C., Akinsola Bolanle, Kebba Touray, Uchendu Uchendu, Baldeh Ignatius, Usman N Ikumapayi, Ikumapayi, Usman N, Touray, Kebba, Levine, Orin S, Orin S Levine, Usuf Effua, Lee, Ellen, Ignatius Baldeh, Richard A Adegbola, Bolanle Akinsola, Saha Debasish, Momodou Jasseh, Sambou, Sana, Levine Orin S., Grant A Mackenzie, Knoll, Maria Deloria, Andre Wattiaux, Baldeh, Ignatius, Mackenzie, Grant A, Knoll Maria Deloria, Adegbola Richard A., Touray Kebba, Usuf, Effua   +55 more
core   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Empirical Bayesian models for analysing molecular serotyping microarrays

, 2011
Background Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assays.
Hinds Jason, Richard Newton, Newton Richard, Hinds, J, Wernisch, L, Lorenz Wernisch, Jason Hinds, Wernisch Lorenz, Newton, R   +8 more
core   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Prevalence of antibodies to four different rotavirus strains in different age groups of cattle [PDF]

, 1990
Neutralizing antibody titers to four bovine rotavirus strains, representing three serotypes, were measured in 160 sera from cattle of different age groups.
Sidoti, Josette, Eichhorn, Werner, Büssow, Harald, Sotek, Jan   +3 more
core  

High levels of recombination among Streptococcus pneumoniae isolates from the Gambia. [PDF]

, 2011
We carried out multilocus sequence typing (MLST) on 148 pneumococcal carriage isolates collected from children
Bishop, CJ, Donkor, ES, Wren, B, C. J. Bishop, M. Antonio, K. A. Gould, Hanage, WP, W. P. Hanage, Hinds, J, Antonio, M, E. S. Donkor, Gould, KA, J. Hinds, Gould, K, B. Wren   +14 more
core   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Emerging non-PCV13 serotypes of noninvasive Streptococcus pneumoniae with macrolide resistance genes in northern Japan

New Microbes and New Infections, 2016
In Japan, the 7-valent pneumococcal conjugate vaccine (PCV7) was introduced to the nation's routine immunization program in April 2013 and was replaced by the 13-valent pneumococcal conjugate vaccine (PCV13) in November 2013.
M. Kawaguchiya, N. Urushibara, M.S. Aung, S. Morimoto, M. Ito, K. Kudo, A. Sumi, N. Kobayashi   +7 more
doaj   +1 more source

Microarray for serotyping of Bartonella species [PDF]

BMC Microbiology, 2007
AbstractBackgroundBacteria of the genusBartonellaare responsible for a large variety of human and animal diseases. Serological typing ofBartonellais a method that can be used for differentiation and identification ofBartonellasubspecies.ResultsWe have developed a novel multiple antigenic microarray to serotypeBartonellastrains and to select poly and ...
Raoult Didier, Nappez Claude, Bonhomme Cyrille J   +2 more
openaire   +3 more sources

Virulence properties and serotypes of Shiga toxin-producing Escherichia coli from healthy Australian cattle [PDF]

, 2002
The virulence properties and serotypes of complex Shiga toxin-producing Escherichia coli (cSTEC) were determined in two studies of healthy cattle in eastern Australia. In the first, a snapshot study, 84 cSTEC isolates were recovered from 37 of 1,692 (2.2%
Bettelheim, Karl A., Gill, Paul, Hornitzky, Michael A., Djordjevic, Steven P., Vanselow, Barbara A., Corney, Bruce, Bailey, Graham, Walker, Keith   +7 more
core   +1 more source