Virus Antibody Dynamics in Primary and Secondary Dengue Infections [PDF]
arXiv, 2012 Dengue viral infections show unique infection patterns arising from its four serot- ypes, (DENV-1,2,3,4). Its effects range from simple fever in primary infections to potentially fatal secondary infections. We analytically and numerically analyse virus dynamics and humoral response in a host during primary and secondary dengue infection for long ...
arxiv
Genetic affinities within a large global collection of pathogenic Leptospira: implications for strain identification and molecular epidemiology [PDF]
, 2010 Leptospirosis is an important zoonosis with widespread human health implications. The non-availability of accurate identification methods for the individualization of different Leptospira for outbreak investigations poses bountiful problems in the ...
Ahmed, Ahmed +7 more
core
The speciation and genotyping of Cronobacter isolates from hospitalised patients [PDF]
, 2015 The World Health Organization (WHO) has recognised all Cronobacter species as human pathogens. Among premature neonates and immunocompromised infants, these infections can be life-threatening, with clinical presentations of septicaemia, meningitis and ...
[No authors listed] +34 more
core +1 more source
Production of latex agglutination reagents for pneumococcal serotyping
BMC Research Notes, 2013 BackgroundThe current ‘gold standard’ for serotyping pneumococci is the Quellung test. This technique is laborious and requires a certain level of training to correctly perform.
B. Ortika +4 more
semanticscholar +1 more source
Mathematical Modelling to Investigate a Wolbachia Intervention to Reduce Dengue Transmission [PDF]
arXiv, 2017 The introduction of Wolbachia-carrying mosquitoes into the population has recently been proposed as an alternative strategy against dengue. Although laboratory experiments have shown that the Wolbachia bacterium can reduce the levels of dengue virus in mosquitoes, it is also important to assess the performance of Wolbachia in reducing the incidence of ...
arxiv
Serotyping of Streptococcus pneumoniae Based on Capsular Genes Polymorphisms
PLoS ONE, 2013 Streptococcus pneumoniae serotype epidemiology is essential since serotype replacement is a concern when introducing new polysaccharide-conjugate vaccines.
F. Raymond +7 more
semanticscholar +1 more source
Mapping of the Influenza-A Hemagglutinin Serotypes Evolution by the ISSCOR Method [PDF]
arXiv, 2013 Analyses and visualizations by the ISSCOR method of influenza virus hemagglutinin genes of different A-subtypes revealed some rather striking temporal relationships between groups of individual gene subsets. Based on these findings we consider application of the ISSCOR-PCA method for analyses of large sets of homologous genes to be a worthwhile ...
arxiv
Dynamics-based peptide-MHC binding optimization by a convolutional variational autoencoder: a use-case model for CASTELO [PDF]
arXiv, 2020 An unsolved challenge in the development of antigen specific immunotherapies is determining the optimal antigens to target. Comprehension of antigen-MHC binding is paramount towards achieving this goal. Here, we present CASTELO, a combined machine learning-molecular dynamics (ML-MD) approach to design novel antigens of increased MHC binding affinity ...
arxiv
Zoonotic potential of Salmonella enterica carried by pet tortoises [PDF]
, 2017 The prevalence of Salmonella in chelonians is not known in the UK and it is not clear whether such Salmonella strains would be pathogenic for human beings.
Barrow, P A, Bruce, H L, Rycroft, A N
core +1 more source
Dynamics of Dengue with human and vector mobility [PDF]
arXiv, 2014 Dengue is a vector borne disease transmitted to humans by {\it{Aedes Aegypti}} mosquitoes carrying Dengue virus of different serotypes. Primarily an urban epidemic, Dengue exhibits complex spatial and temporal dynamics, influenced by many biological, human and environmental factors.
arxiv