Results 131 to 140 of about 31,748 (307)

Establishment of a Molecular Serotyping Scheme and a Multiplexed Luminex-Based Array for Enterobacter aerogenes

, 2018
Serotyping based on surface polysaccharide antigens is important for the clinical detection and epidemiological surveillance of pathogens. Polysaccharide gene clusters (PSgcs) are typically responsible for the diversity of bacterial surface ...
Xi Guo, Lu Wang, Yao Wang, Min Wang, Bin Liu, Lu Feng, Pan Wu, Min Chen, Tingting Chen   +8 more
core   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Fourth Human Parechovirus Serotype

Emerging Infectious Diseases, 2006
We identified a novel human parechovirus (HPeV) type (K251176-02) from a neonate with fever. Analysis of the complete genome showed K251176-02 to be a new HPeV genotype. Since K251176-02 could not be neutralized with antibodies against known HPeV serotypes 1-3, it should be classified as a fourth HPeV serotype.
Benschop, Kimberley S. M., Schinkel, Janke, Luken, Manon E., van den Broek, Peter J. M., Beersma, Matthias F. C., Menelik, Negassi, van Eijk, Hetty W. M., Zaaijer, Hans L., Vandenbroucke-Grauls, Christina M. J. E., Beld, Marcel G. H. M., Wolthers, Katja C.   +10 more
openaire   +3 more sources

Value of Indirect Hemagglutination and Coagglutination Tests for Serotyping Haemophilus parasuis [PDF]

, 2017
P. 880-882An indirect hemagglutination test (IHA) and a coagglutination test (CA) were evaluated using saline, boiled, and autoclaved extracts for serotyping Haemophilus parasuis.
Río González, María Luisa del, Gutiérrez Martín, César Bernardo, Rodríguez Ferri, Elías Fernando   +2 more
core  

Simplified Microneutralization Test for Serotyping Adenovirus Isolates

, 2001
A simplified microneutralization procedure is described that uses an empirically determined virus challenge dose, a single dilution of antiserum, and observation of cytopathic effect to determine the adenovirus serotype.
Leta K. Crawford-Miksza, David P. Schnurr, Marietta D. Malasig, Gregory C. Gray, Pulak R. Goswami   +4 more
core   +1 more source

Capsular serotyping of Streptococcus pneumoniae using the quellung reaction [PDF]

, 2014
There are over 90 different capsular serotypes of Streptococcus pneumoniae (the pneumococcus). As well as being a tool for understanding pneumococcal epidemiology, capsular serotyping can provide useful information for vaccine efficacy and impact studies.
Habib, M, Satzke, C, Porter, BD
core   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

Prevalencia del Streptococcus agalactiae en maternas usuarias del Hospital Militar Central: Bogotá, (Colombia) año 2010 The prevalence of Streptococcus agalactiae in pregnant women attending the Hospital Militar Central, Bogota, Colombia, 2010

Revista Colombiana de Obstetricia y Ginecología, 2011
Objetivo: establecer la prevalencia del Streptococcus agalactiae en gestantes que asisten al servicio de medicina materno fetal del Hospital Militar Central en el periodo comprendido entre enero 15 de 2010 y septiembre 15 de 2010.
Daniel Alejandro García, María Edith Mojica, Iván Alberto Méndez, Diana Patricia Pachón, Andrés Camilo Prieto, Elisa Victoria Santamaría, Omar Javier Calixto, Cristian Camilo Murcia   +7 more
doaj  

Prevalence and distribution of dengue virus serotypes among seropositive patients at a tertiary care center: A retrospective study

Journal of Indira Gandhi Institute of Medical Sciences
Introduction: Dengue fever, a significant public health threat in tropical and subtropical regions, is caused by any of the five dengue virus serotypes (DENV-1 to DENV-5).
Nusrat Jahan, Nidhi Prasad, Bhim Ram, Kalichamy Alagarasu, Shishir Kumar, Vidyut Prakash, Shivani Agrawal   +6 more
doaj   +1 more source