Results 191 to 200 of about 25,004 (263)

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor   +4 more
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

open access: yesInternational Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim   +22 more
wiley   +1 more source

SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in <i>Streptococcus pneumoniae</i>. [PDF]

open access: yesMicrob Genom
Lorenz O   +13 more
europepmc   +1 more source

Coxsackievirus B Infections Are Associated With the Risk of Islet Autoimmunity in Children With Strong Genetic Susceptibility to Type 1 Diabetes—Results From the TRIGR Divia Study

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims Especially, the coxsackievirus B group of enteroviruses has been linked to the development of islet autoimmunity and type 1 diabetes in genetically susceptible individuals. Our aim was to study the possible associations of 10 different microbial infections with islet autoimmunity in a large international prospective study.
Maarit Oikarinen   +14 more
wiley   +1 more source

Baat‐Deficient Mice Recapitulate Elevated 7α‐Hydroxy‐3‐Oxo‐4‐Cholestenoic Acid Observed in a Japanese Patient With BAAT Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACTBile acid Coenzyme A: amino acid N‐acyltransferase (BAAT) catalyzes the conjugation of bile acids with taurine or glycine, a process essential for bile acid solubility and intestinal lipid absorption. Mutations in BAAT cause an inborn error of bile acid metabolism, typically characterized by reduced conjugated bile acids and fat‐soluble vitamin
Soma Koga   +6 more
wiley   +1 more source

Salmonella enterica serovars co‐exist sporadically and at low abundance in US mid‐Atlantic irrigation ponds

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 12, Page 7015-7022, September 2026.
Abstract BACKGROUND Spring or rain‐fed ponds are frequent features on US mid‐Atlantic farms. The need to conduct preharvest agricultural water assessments to identify microbial hazards, as required by the US Produce Safety Rule, highlights knowledge gaps pertaining to pond water adequacy for vegetable production.
Shirley A Micallef   +4 more
wiley   +1 more source

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