Results 221 to 230 of about 42,797 (295)

SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in <i>Streptococcus pneumoniae</i>. [PDF]

open access: yesMicrob Genom
Lorenz O   +13 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel   +2 more
wiley   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

open access: yesAdvanced Materials, Volume 38, Issue 17, 20 March 2026.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

Label‐Free Detection of PSA Using Laser‐Induced Graphene/ZnO Nanorod‐Based Impedimetric Immunosensors

open access: yesAdvanced Sensor Research, Volume 5, Issue 3, March 2026.
A label‐free impedimetric immunosensor based on laser‐induced graphene decorated with ZnO nanorods is developed for prostate‐specific antigen detection. Antibody adsorption on ZnO enables clinically relevant sensitivity and an unconventional “signaling‐off” response, where charge‐transfer resistance decreases upon antigen binding, challenging ...
Maria S. Soares   +4 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

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