SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in <i>Streptococcus pneumoniae</i>. [PDF]
Lorenz O +13 more
europepmc +1 more source
Quinic Acid and Synthetic Derivatives in Medicinal Chemistry
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel +2 more
wiley +1 more source
A two-year study of <i>Salmonella</i> in four natural watersheds highlights the need for increased environmental <i>Salmonella</i> surveillance to close the One Health loop. [PDF]
Smith JC +4 more
europepmc +1 more source
Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
Epidemiology, serovar distribution and spatiotemporal patterns of Salmonella foodborne infections in Liaoning Province, China, 2014-2024: an analysis of sentinel surveillance data. [PDF]
Yu X +6 more
europepmc +1 more source
A label‐free impedimetric immunosensor based on laser‐induced graphene decorated with ZnO nanorods is developed for prostate‐specific antigen detection. Antibody adsorption on ZnO enables clinically relevant sensitivity and an unconventional “signaling‐off” response, where charge‐transfer resistance decreases upon antigen binding, challenging ...
Maria S. Soares +4 more
wiley +1 more source
Towards decentralization of <i>Salmonella</i> serotyping and risk assessment in poultry production environments with nanopore sequencing. [PDF]
Karunarathna R +5 more
europepmc +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source

