Results 271 to 280 of about 69,583 (343)

Hippocampal Chandelier Cells Modulate Seizure Susceptibility and Severity

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
The axon initial segment (AIS), crucial for action potential initiation, serves as a prime locus for controlling network activity. Chandelier Cells (ChCs), evolved in the mammals, intricately target AISs, acting as gatekeepers for neuronal firing. Diminishing ChC input makes animals more prone to developing seizures, whereas fortifying this connection ...
Yang Li   +7 more
wiley   +1 more source

Serotyping of <i>Actinobacillus pleuropneumoniae</i> based on whole genome sequencing: validation of a bioinformatic tool. [PDF]

open access: yesMicrob Genom
Angen Ø   +9 more
europepmc   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu   +5 more
wiley   +1 more source

Serotype specific qRT-PCR for novel BTV serotypes

open access: yes
D5.1: Serotype specific qRT-PCR for novel BTV serotypes (Partner 1, 2, 4, 5, 12, 16). (M18)
openaire   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna   +11 more
wiley   +1 more source

Fluorescent Nanodiamonds for Lateral Flow Assays Enhanced by Magnetic Modulation: From Synthesis to Application

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 1, January 2026.
This review examines the use of fluorescent nanodiamonds (FNDs) in lateral flow assays (LFAs) for advanced diagnostics. FNDs offer superior photostability and biocompatibility compared to traditional labels. The review covers FND synthesis, and integration with detection systems to enhance performance.
Jihoon Shin   +10 more
wiley   +1 more source

Prevalence of bluetongue serotype 3 following the 2023 epidemic and associated risk factors in Dutch dairy cattle [PDF]

open access: gold
K.M.J.A. van den Brink   +7 more
openalex   +1 more source

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