Results 71 to 80 of about 134,892 (370)

Quantitative Prediction of Linear B-Cell Epitopes [PDF]

Biomedical Statistics and Informatics. Vol. 2, No.1, 2017, pp.1-3, 2017
In scientific literature, there are many programs that predict linear B-cell epitopes from a protein sequence. Each program generates multiple B-cell epitopes that can be individually studied. This paper defines a function called that combines results from five different prediction programs concerning the linear B-cell epitopes (ie., BebiPred ...
arxiv   +1 more source

Multi-Serotype Pneumococcal Nasopharyngeal Carriage Prevalence in Vaccine Naïve Nepalese Children, Assessed Using Molecular Serotyping

PLoS ONE, 2015
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
R. Kandasamy, M. Gurung, Anushil K Thapa, Susan Ndimah, N. Adhikari, D. Murdoch, D. Kelly, Denise E. Waldron, K. Gould, S. Thorson, S. Shrestha, J. Hinds, A. Pollard   +12 more
semanticscholar   +1 more source

Upconversion‐Based Remote Deep Brain Modulation for Therapeutic Dissection of Parkinson's Disease

Advanced Therapeutics, EarlyView.
An upconversion‐based wireless optogenetic strategy enables an all‐optical deep brain modulation solution for treating Parkinson's disease in rodent animals without using electronics or any tethered cables, providing experimental evidence supporting a therapeutic mechanism of STN‐DBS by disruption of anterograde signal transmission along the indirect ...
Wenchong Zhang, Xudong Lin, Kai Xie, Zixun Wang, Tianying Sun, Zhen Xu, Haibing Yue, Xi Chen, Qinghai Liao, Ming Liu, Wing Ho Yung, Jufang He, Feng Wang, Peng Shi   +13 more
wiley   +1 more source

One-step real-time RT-PCR assays for serotyping dengue virus in clinical samples

BMC Infectious Diseases, 2015
BackgroundDengue is one of the leading causes of morbidity in tropical and subtropical regions and infection with any of the four dengue virus serotypes (DENV1-4) result in a wide range of clinical manifestations.
E. Alm, G. Lindegren, K. Falk, N. Lagerqvist   +3 more
semanticscholar   +1 more source

Analysis of Collection of Hemolytic Uremic Syndrome–associated Enterohemorrhagic Escherichia coli

Emerging Infectious Diseases, 2008
Multilocus sequence typing of 169 non-O157 enterohemorrhagic Escherichia coli (EHEC) isolated from patients with hemolytic uremic syndrome (HUS) demonstrated 29 different sequence types (STs); 78.1% of these strains clustered in 5 STs.
Alexander Mellmann, Martina Bielaszewska, Robin Köck, Alexander W. Friedrich, Angelika Fruth, Barbara Middendorf, Dag Harmsen, M. Alexander Schmidt, Helge Karch   +8 more
doaj   +1 more source

Serotype composition of Streptococcus pneumoniae in children with respiratory infections, optimization of molecular assessment methods

Антибиотики и Химиотерапия, 2022
The paper presents optimized methods for PCR and sequence typing of Streptococcus pneumoniae. The serotype composition of pneumococci isolated from children under 5 years of age with infections of the upper respiratory tract was analyzed using optimized ...
E. V. Nikitina, I. A. Tsvetkova, O. S. Kalinogorskaya, V. V. Gostev, S. S. Belanov, A. S. Mokhov, E. L. Kalisnikova, V. A. Ageevets, D. P. Gladin, S. V. Sidorenko   +9 more
doaj   +1 more source

Markovian approach to tackle the interaction of simultaneous diseases [PDF]

Phys. Rev. E 100, 062308 (2019), 2019
The simultaneous emergence of several abrupt disease outbreaks or the extinction of some serotypes of multi-strain diseases are fingerprints of the interaction between pathogens spreading within the same population. Here, we propose a general and versatile benchmark to address the unfolding of both cooperative and competitive interacting diseases.
arxiv   +1 more source

Microarray for serotyping of Bartonella species [PDF]

BMC Microbiology, 2007
AbstractBackgroundBacteria of the genusBartonellaare responsible for a large variety of human and animal diseases. Serological typing ofBartonellais a method that can be used for differentiation and identification ofBartonellasubspecies.ResultsWe have developed a novel multiple antigenic microarray to serotypeBartonellastrains and to select poly and ...
Cyrille J. Bonhomme, Didier Raoult, Claude Nappez   +2 more
openaire   +4 more sources

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Experience with the quantitative lytA gene real-time polymerase chain reaction for the detection of Streptococcus pneumoniae from pediatric whole blood in Pakistan

Biomedical and Biotechnology Research Journal, 2017
Background: We present our experience with optimization and diagnostic use of quantitative real-time polymerase chain reaction (PCR) targeting the lytA gene of Streptococcus pneumoniae for the detection of S. pneumoniae in whole blood of children
Furqan Kabir, Sahrish Muneer, Adil Kalam, Ana Sami, Shahida Qureshi, Aneeta Hotwani, Atif Riaz, Syed Mohiuddin, Mohammad Tahir Yousafzai, Sara Hussain, Asad Ali, Sadia Shakoor   +11 more
doaj   +1 more source