Results 81 to 90 of about 144,200 (356)

The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies

PLoS Medicine, 2015
Background The pneumococcus is a diverse pathogen whose primary niche is the nasopharynx. Over 90 different serotypes exist, and nasopharyngeal carriage of multiple serotypes is common.
C. Satzke, E. Dunne, Barbara D. Porter, K. Klugman, E. Mulholland   +4 more
semanticscholar   +1 more source

Serotype epidemiology and multidrug resistance patterns of Salmonella enterica infecting humans in Italy [PDF]

, 2016
BACKGROUND: Salmonella enterica is the zoonotic agent most frequently responsible for foodborne infections in humans worldwide. In this work the presence of S.
Bettanello, Sabrina, De Canale, Ettore, Frasson, Ilaria, Palu', Giorgio, Richter, Sara   +4 more
core   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

One-step real-time RT-PCR assays for serotyping dengue virus in clinical samples

BMC Infectious Diseases, 2015
BackgroundDengue is one of the leading causes of morbidity in tropical and subtropical regions and infection with any of the four dengue virus serotypes (DENV1-4) result in a wide range of clinical manifestations.
E. Alm, G. Lindegren, K. Falk, N. Lagerqvist   +3 more
semanticscholar   +1 more source

Salmonella enterica subsp. enterica along the pig commodity chain in Vietnam [PDF]

, 2008
Foodborne diseases are a particularly important concern in the current Vietnamese context, shortly after accession to the WTO, not only for public health reasons, but also because of the global evolution of consumer demand and habits, the production ...
Bily, L., Chu-Ky, Son, Denis, Martine, Fravalo, P., Gardon, C., Hoang Vu Quang,, Labbe, A., Le Bas, Cédric, Le Thanh Mai,, Minh, N.B., Nguyen Manh Cuong,, Patin, A., Thanh, Nguyen T., Tran Thi Hanh,, Vu Trong Binh,   +14 more
core  

Effect of the enrichment medium on the detection and diversity of Salmonella from porcine duodenal content [PDF]

, 2013
This study assesses the effect of the enrichment medium used on the isolation of Salmonella from the duodenal content of naturally infected slaughter pigs.
De Busser, Emily Valerie, De Zutter, Lieven, Dewulf, Jeroen, Houf, Kurt, Maes, Dominiek   +4 more
core   +2 more sources

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Comparison of the biotypes of Yersinia enterocolitica isolated from pigs, cattle and sheep at slaughter and from humans with yersiniosis in Great Britain during 1999-2000 [PDF]

, 2004
Aims: To investigate the relationship between livestock carriage of Yersinia enterocolitica and human disease. The biotypes/serotypes of strains recovered from the faeces of pigs, cattle and sheep at slaughter during a national survey in Great Britain in
Atanassova V., Bottone E.J., Falcao J.P., Fantasia M., Fenwick S.G., Floccari M.E., Food Standards Agency, Fredriksson-Ahomaa M., Fredriksson-Ahomaa M., Fukushima H., Gourdon F., Grant T., Jones T.F., Prentice M., Schiemann D.A., Tennant S.M., Watabe M.   +16 more
core   +2 more sources

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Experience with the quantitative lytA gene real-time polymerase chain reaction for the detection of Streptococcus pneumoniae from pediatric whole blood in Pakistan

Biomedical and Biotechnology Research Journal, 2017
Background: We present our experience with optimization and diagnostic use of quantitative real-time polymerase chain reaction (PCR) targeting the lytA gene of Streptococcus pneumoniae for the detection of S. pneumoniae in whole blood of children
Furqan Kabir, Sahrish Muneer, Adil Kalam, Ana Sami, Shahida Qureshi, Aneeta Hotwani, Atif Riaz, Syed Mohiuddin, Mohammad Tahir Yousafzai, Sara Hussain, Asad Ali, Sadia Shakoor   +11 more
doaj   +1 more source