Results 131 to 140 of about 142,377 (309)
Oral mineralocorticoid antagonists for recalcitrant central serous chorioretinopathy
, 2015 Eric K Chin, David RP Almeida, C Nathaniel Roybal, Philip I Niles, Karen M Gehrs, Elliott H Sohn, H Culver Boldt, Stephen R Russell, James C FolkDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USAPurpose: To evaluate ...
Russell SR +8 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Forgotten exogenous corticosteroid as a cause of central serous chorioretinopathy
, 2008 Paul W Hardwig1, Amila O Silva2, Jose S Pulido11Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA; 2Kaiser Permanente Fontana Medical Center, Fontana, CA, USAAbstract: Central serous chorioretinopathy (CSCR) is an idiopathic ocular condition ...
Jose S Pulido +2 more
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Risk factors for central serous chorioretinopathy: A case–control study
, 2004 To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR). Retrospective, case–control study. Participants and controls: 312 cases and 312 controls. By use of a multivariate analysis, the previously described
Haimovici, Robert +5 more
core +1 more source
Thoughts on Serous Polyæmia [PDF]
The American Journal of the Medical Sciencesn ...
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Serous retinal detachment after trabeculectomy in angle recession glaucoma
, 2015 An 18-year-old male with 360 degree angle recession after blunt trauma in his right eye developed uncontrolled intraocular pressure (IOP) despite four antiglaucoma medications (AGM) with advancing disc damage.
Roy, Avik Kumar +3 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Serous cystic neoplasms of the pancreas
, 2005 Pancreatic serous neoplasms are rare but account for the most common type of pancreatic cystic neoplasms. The vast majority of serous cystic tumours are benign (serous cystadenoma).
Chetty, R +3 more
core +1 more source