Results 251 to 260 of about 20,613 (283)

Serpins Save Cells

Science's STKE, 2007
Biologically active proteases are held in check in part by a family of peptidase inhibitors known as serpins. Most serpins are secreted proteins, but some are intracellular proteins implicated in regulating lysosomal proteases. Knockout mice have failed to reveal the biological roles of these inhibitors, though--possibly because mice have ...
openaire   +2 more sources

Maspin: A Tumor Suppressing Serpin

1996
Maspin, a serpin found in mammary epithelial cells, has been shown to have tumor suppressor activity. The gene is expressed in normal human mammary epithelial cells but down-regulated in invasive breast carcinomas. Similar patterns of expression at the RNA and protein levels are seen by Northern analysis with cells grown in culture and by ...
R, Sager, S, Sheng, P, Pemberton, M J, Hendrix   +3 more
openaire   +3 more sources

Serpins

1997
Stuart R. Stone, James C. Whisstock, Stephen P. Bottomley, Paul C. R. Hopkins   +3 more
openaire   +2 more sources

Overview of Serpins and Their Roles in Biological Systems.

Methods in molecular biology, 2018
A. Lucas, Jordan R. Yaron, Liqiang Zhang, Sriram Ambadapadi   +3 more
semanticscholar   +1 more source

Serpins: Development for Therapeutic Applications.

Methods in molecular biology, 2018
A. Lucas, Jordan R. Yaron, Liqiang Zhang, C. Macaulay, G. McFadden   +4 more
semanticscholar   +1 more source

The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins

Journal of Biological Chemistry, 2001
G. Silverman, P. Bird, R. Carrell, F. Church, P. Coughlin, P. Gettins, J. Irving, D. Lomas, C. J. Luke, R. Moyer, P. Pemberton, E. Remold-O’Donnell, G. Salvesen, J. Travis, J. Whisstock   +14 more
semanticscholar   +1 more source

Arabidopsis thaliana serpins AtSRP4 and AtSRP5 negatively regulate stress-induced cell death and effector-triggered immunity induced by bacterial effector AvrRpt2.

Physiologia Plantarum : An International Journal for Plant Biology, 2017
L. Bhattacharjee, Deepjyoti Singh, J. K. Gautam, A. Nandi   +3 more
semanticscholar   +1 more source

Deconvoluting serpins

Nature Structural & Molecular Biology, 1994
Robert J. Fletterick, Mary E. McGrath
openaire   +1 more source

Role of heparin and non heparin binding serpins in coagulation and angiogenesis: A complex interplay.

Archives of Biochemistry and Biophysics, 2016
Teena Bhakuni, Mohammad Farhan Ali, Irshad Ahmad, Shadabi Bano, Shoyab Ansari, M. A. Jairajpuri   +5 more
semanticscholar   +1 more source

Serpins

RCSB Protein Data Bank, 2004
openaire   +1 more source