Results 201 to 210 of about 3,295,861 (246)

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

open access: yesAdvanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin   +9 more
wiley   +1 more source

Gel‐Free Capture of Microvolt‐Level Neural Signatures Via a 3D Monolithic Carbon Fiber Dry Electrode

open access: yesAdvanced Science, EarlyView.
A compressible carbon fiber/PEDOT:PSS electrode enables gel‐free contact at hairy scalp sites. Its conductive porous framework supports low interfacial impedance and retains contact performance after repeated mechanical and sweat‐related challenges.
Haoxuan Sun   +11 more
wiley   +1 more source

Endoscopic Surveillance in Serrated Polyposis Syndrome, Two or Three-Year Intervals: A Non-inferiority Randomized Trial. [PDF]

open access: yesDig Dis Sci
López-Vicente J   +10 more
europepmc   +1 more source

RUNX1‐Mediated Hypoxic Signaling Impairs Myogenesis and Promotes Fibrosis in Myopathies

open access: yesAdvanced Science, EarlyView.
Myofiber overgrowth was associated with reduced blood flow and a potential hypoxic state in broiler breast muscle, accompanied by increased RUNX1 expression. Elevated RUNX1 impaired myogenic regeneration, promoted fibrosis, and disrupted the signaling niche required for efficient muscle repair, contributing to pathological degeneration in Wooden Breast
Liang Zhao   +4 more
wiley   +1 more source

Precision ventral extraction of implanted mouse brains: A protocol. [PDF]

open access: yesSTAR Protoc
El-Fayomi L   +2 more
europepmc   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

open access: yesAdvanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima   +18 more
wiley   +1 more source

Accurate and Scalable Classification of Colonoscopy Neoplasia Using Machine Learning and Natural Language Processing. [PDF]

open access: yesClin Transl Gastroenterol
Broderick B   +8 more
europepmc   +1 more source

DTX3 Suppresses the NPM3–RUVBL1 Axis to Inhibit Homologous Recombination Repair and Abrogate Tumor Radioresistance

open access: yesAdvanced Science, EarlyView.
Deltex 3 (DTX3) catalyzes K27‐linked ubiquitination of nucleophosmin 3 to disrupt homologous recombination repair and reverse tumor radioresistance. Low DTX3 predicts poor survival and radiotherapy recurrence, serving as a radiosensitizing therapeutic target.
Jia‐Hao Xiao   +9 more
wiley   +1 more source

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