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Serrated Polyps and Serrated Polyposis Syndrome

Cirugía Española (English Edition), 2013
Serrated polyps of the colorectum are a heterogeneous group of lesions with potential malignant transformation through the «serrated pathway» of carcinogenesis. The discovery of these lesions has been a paradigm shift in the concept of the adenoma-carcinoma sequence, so that up to 30% of tumors develop through this pathway.
Sabela, Carballal   +2 more
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Serrated adenomas

Current Gastroenterology Reports, 2009
Serrated adenomas are categorized as sessile serrated adenomas (SSAs) and traditional serrated adenomas (TSAs). SSAs are more prevalent in the proximal colon and lack classic dysplasia, whereas TSAs are more prevalent in the rectosigmoid and have cytologic dysplasia.
Wilfredo E, De Jesus-Monge   +2 more
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Serrated lesions of the appendix in serrated polyposis patients

Pathology, 2016
Patients with serrated polyposis develop multiple serrated polyps throughout the large bowel: hyperplastic polyps (HP), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). The frequency and the characteristics of serrated lesions of the appendix have not been reported in serrated polyposis patients.
Bettington, Mark   +2 more
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Serrated

Ploughshares, 2023
Abstract: The Summer 2023 Issue. Ploughshares is an award-winning journal of new writing. Since 1971, Ploughshares has discovered and cultivated the freshest voices in contemporary American literature, and now provides readers with thoughtful and entertaining literature in a variety of formats.
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The Frontiers of Serrated Polyps

American Journal of Surgical Pathology, 2021
The serrated pathway of carcinogenesis has been the subject of intense investigation over the past 2 decades, but many gaps in our understanding still need to be resolved. Serrated polyp precursors include hyperplastic polyps, sessile serrated polyps, and traditional serrated adenomas.
Phoenix D, Bell   +2 more
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Current Approaches in Managing Colonic Serrated Polyps and Serrated Polyposis

Annual Review of Medicine, 2022
For decades, conventional adenomas were the only known precursor lesions of colorectal cancer (CRC). Accordingly, education and research regarding CRC prevention were mainly focused on adenomas. The groundbreaking discovery that serrated polyps (SPs) also have the potential to develop into CRCs, and seem to account for a considerable proportion of ...
David E F W M, van Toledo   +2 more
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Serrated Colorectal Neoplasia

Surgical Pathology Clinics, 2010
Until very recently, there was general acceptance in the pathology community that all serrated lesions of the colon and rectum without overt cytologic dysplasia were hyperplastic polyps and had no malignant potential. Although there are still several unanswered questions in regard to the relationship between the various serrated lesions, there is a ...
Dale C, Snover, Kenneth P, Batts
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Serrated Marine Nose

New England Journal of Medicine, 2017
A 37-year-old woman taking adalimumab for ankylosing spondylitis presented with ulcerations with a hemorrhagic crust over her nose. Two waterborne organisms grew in biopsy samples obtained from the ulcers.
Schlapbach C, Sendi P
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Serrated and Non-Serrated Precursor Lesions of Colorectal Cancer

Digestive Diseases, 2014
Although often viewed as a single disease, colorectal cancer more accurately represents a family of diseases with different precursor lesions. Conventional (tubular, tubulovillous and villous) adenomas are the most common neoplastic lesions occurring in the large intestine.
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