Results 251 to 260 of about 1,288,749 (348)

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

Advanced Science, EarlyView.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo, Qiancheng Mao, Xinyu Fang, Liuxuan Huang, Haoquan Tian, Wenguang Yang, Feiyue Zhou, Ke Ma   +7 more
wiley   +1 more source

Research advances in SERS-based sensing platforms for multiplex mycotoxin detection in feed. [PDF]

Nanoscale Adv
Chen Y, Chen R, Wang H, Zhao J, Pan D, Yang L, Tang X, Xiong B.   +7 more
europepmc   +1 more source

Selective Removal of the Selenocysteine tRNA^[Ser]Sec Gene (Trsp) in Mouse Mammary Epithelium

, 2003
Easwari Kumaraswamy, Bradley A. Carlson, Fanta Morgan, Keiko Miyoshi, Gertraud W. Robinson, Dan Su, Shulin Wang, Eileen Southon, Lino Tessarollo, Byeong Jae Lee, Vadim N. Gladyshev, Lothar Hennighausen, Dolph L. Hatfield   +12 more
openalex   +1 more source

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

A Point-of-Use Assay Based on Surface-Enhanced Raman Spectroscopy for Rapid Determination of Triclosan in Environmental Water and Mouthwash. [PDF]

ACS Omega
Wei H, Gao G, Liu L, Pan H, Zhang M, Liu T, Meng X, Zhang Y, Feng R, Zhao L, Shang M.   +10 more
europepmc   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

Advanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu, Lingyu Ke, Ruize Sun, Xiaoling Chen, Mei Zhou, Olaf R. P. Bininda‐Emond, Chengbang Ma, Yangyang Jiang, Tao Wang, Chris Shaw, Lei Wang, Tianbao Chen, Alideertu Dong   +12 more
wiley   +1 more source

Engineering nanopore in monolayer WS₂ for single-molecule imaging on the atomic-scale flat 2D surfaces. [PDF]

Sci Adv
He H, Zhao M, Xu H, Chang L, Jiang Y, Bai Y, Wang C, Nong H, Ma L, Gan L, Zhang T, Kang F, Liu B, Lei Y.   +13 more
europepmc   +1 more source

El plasmidio críptico pTLC de Vibrio cholerae podría ser un vestigio evolutivo del genoma de un fago filamentoso

, 2007
Lourdes Proenza, Edith Suzarte, Talena Ledón, Karen Marrero, Boris L. Rodrı́guez, Rafael Fando, Javier Campos   +6 more
openalex   +1 more source

SERS enhancements via periodic arrays of gold nanoparticles on silver film structures

, 2009
Jason M. Montgomery, Alexandra Joshi‐Imre, U. Welp, V. K. Vlasko‐Vlasov, Stephen K. Gray   +4 more
openalex   +1 more source