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Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis [PDF]

open access: yesEndocrine Reviews, 2004
Spermatogenesis is the process by which a single spermatogonium develops into 256 spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the epithelial cycle were first described, reproductive biologists have been in pursuit of one question: How can a spermatogonium traverse the epithelium, while at the same time ...
C Yan Cheng   +2 more
exaly   +3 more sources
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Morphological evidence for calcium stores at Sertoli-Sertoli and Sertoli-spermatid interrelations

Cell Biology International Reports, 1985
Potassium pyroantimonate technique has been employed to localize calcium ultrastructurally at Sertoli-Sertoli and Sertoli-spermatid junctional specializations. Identification of Ca++ as the major cation precipitated was performed by EGTA sensitivity and X-ray microprobe analysis.
E, Franchi, M, Camatini
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Three‐dimensional reconstruction of a rat stage V Sertoli cell: II. Morphometry of Sertoli–Sertoli and Sertoli–germ‐cell relationships

American Journal of Anatomy, 1983
AbstractSertoli–Sertoli and Sertoli–germ‐cell configurational relationships were studied using morphometric techniques and direct measurements as obtained from micrographs used to reconstruct a model of a rat stage V Sertoli cell. Regional areas of the Sertoli cell surface, which faced germ cells, other Sertoli cells, or noncellular structures, were ...
J E, Weber   +3 more
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The sertoli cell in lizards

Journal of Ultrastructure Research, 1983
Sertoli cells of lizards are characterized by variable size, abundant smooth and rough endoplasmic reticulum, multivesicular bodies, lipid vacuoles probably related to the spermatogenic cycle, and mitochondria of normal size. The cytoskeleton contains actin, particularly abundant in the cell periphery, vimentin all around the nucleus and throughout the
B, Baccetti   +3 more
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Sertoli cell types in the Sertoli‐cell‐only syndrome: relationships between Sertoli cell morphology and aetiology

Histopathology, 1990
Histological study of testicular biopsies from infertile men showing Sertoli‐cell‐only tubules due to hypogonadotropic hypogonadism, cryptorchidism, oestrogen treatment, chemotherapy or Del Castillo's syndrome, revealed four types of Sertoli cells: (1) normal adult mature cells showing an indented nucleus, grossly triangular in shape with a prominent ...
M, Nistal, F, Jimenez, R, Paniagua
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The Sertoli Cell Cytoskeleton

2009
The cytoskeleton of terminally differentiated mammalian Sertoli cells is one of the most elaborate of those that have been described for cells in tissues. Actin filaments, intermediate filaments and microtubules have distinct patterns of distribution that change during the cyclic process of spermatogenesis. Each of the three major cytoskeletal elements
A Wayne, Vogl   +2 more
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Sertoli Cell Tumour in a Cat

Journal of Veterinary Medicine Series A, 2004
SummaryA Sertoli cell tumour occurred in a cryptorchid testis of a 1‐year‐old cat with no signs of feminization. The tumour showed intratubular growth without interstitial infiltration and the neoplastic cells appeared polymorphous and vacuolated. Mitotic figures were rare.
BENAZZI, CINZIA   +2 more
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Sertoli‐Sertoli junctions and Sertoli‐spermatid junctions after efferent ductule ligation and lanthanum treatment

American Journal of Anatomy, 1977
AbstractSeminiferous tubules, partially dilated by ligation of the efferent ductules, were examined after treatment with lanthanum. Lanthanum penetrated the intercellular spaces of the seminiferous epithelium, but only to the level of the Sertoli‐Sertoli junctions.
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Spermatogenesis and the Sertoli Cell

1983
The pioneering studies by Greep and co-workers (Greep et al. 1936) established that two gonadotrophic hormones FSH and LH could be extracted from mammalian pituitary glands. From these observations and the studies of Smith on hypophysectomised animals (Smith 1930) the concept was developed that FSH acted on the seminiferous tubules and LH on the ...
K A, Rich, D M, de Kretser
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Sertoli Cell

2018
There is more than a century and a half that the polarized Sertoli cell which extends from the base of the seminiferous tubule to its lumen has been identified as being a “nurse cell” for germ cells. This Sertoli cell nursing function relies on a cytosqueleton displaying all possible properties of plasticity to adapt to the cyclicity of spermatogenesis,
Jégou, Bernard, Rolland, Antoine D.
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