Bilateral Leydig Cell Tumor in a Capuchin Monkey (Sapajus apella): Case Report
ABSTRACT Leydig cell tumors (LCTs) are uncommon in nonhuman primates (NHPs). A bilateral LCT was identified in a 20‐year‐old male capuchin monkey (Sapajus apella) maintained under human care. Ultrasonography revealed a right testicular nodule, while necropsy identified bilateral testicular masses. Histopathology confirmed bilateral LCT.
Ewerton Lourenço Barbosa Favacho +6 more
wiley +1 more source
Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro. [PDF]
Scalzone A +4 more
europepmc +1 more source
Abstract To describe clinical presentation and genetic findings in a cohort of infants with congenital hypogonadotropic hypogonadism (CHH) diagnosed before 2 years of age. From a large cohort of patients who underwent next‐generation sequencing (NGS) for CHH between 2019 and 2025, we identified all patients tested at ≤2 years of age.
Karine Aouchiche +16 more
wiley +1 more source
PTD-FNK Alleviated Heat Stress-Induced Apoptosis of Boar Sertoli Cells via the PI3K/AKT Pathway. [PDF]
Huang Q +11 more
europepmc +1 more source
Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez +3 more
wiley +1 more source
Glycogen and lactate metabolism in mouse fetal Sertoli cells sustain the germ line. [PDF]
Estermann MA +7 more
europepmc +1 more source
Humanin ameliorates diabetes‐induced testicular damage in a streptozotocin‐induced mouse model
Abstract Diabetes mellitus is a major metabolic disorder closely associated with oxidative stress and male reproductive dysfunction. Humanin, a mitochondria‐derived peptide, has been reported to exert cytoprotective, anti‐apoptotic and antioxidant effects in various disease models; however, its role in diabetes‐induced testicular damage remains unclear.
Munevver Gizem Hekim +2 more
wiley +1 more source
Sertoli cells as a hub in testicular development and male reproductive. [PDF]
Feng X +9 more
europepmc +1 more source
Messenger RNA delivery into Sertoli cells restores fertility to congenitally infertile male mice. [PDF]
Kanatsu-Shinohara M +9 more
europepmc +1 more source
Effect of Ewe Nutritional Restriction During Gestation on the Number of Sertoli Cells in the Offspring: A Meta-Analysis. [PDF]
Espinosa-Martínez MA +2 more
europepmc +1 more source

