Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras +8 more
wiley +1 more source
Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]
This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
core +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
PharmGKB summary: sertraline pathway, pharmacokinetics
Department of Biomedical Data Sciences, Stanford University, Stanford, California, Department of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, Department of Pediatrics, University of Cincinnati ...
Rachel Huddart +7 more
semanticscholar +1 more source
Cognitive Behavioral Therapy in Movement Disorders. A Review [PDF]
In addition to motor symptoms, patients with movement disorders often complain of psychiatric disturbances, including mood, anxiety, and impulse-control disorders and psychosis.
Berardelli, Alfredo +5 more
core +1 more source
A Natural Resource‐Based View of Circular Economy Practices in the Pharmaceutical Industry
ABSTRACT Pharmaceutical industry is facing escalating environmental sustainability issues including gaseous emissions, waste generation, and excessive consumption of energy and non‐renewable materials. Nevertheless, the adoption of sustainable business models such as the circular economy (CE) is still in its infancy in this sector due to complex ...
Amna Farrukh, Muhammad Sohaib Sajjad
wiley +1 more source
With increased social pressure, individuals face a high risk of depression. Subsequently, depression affects cognitive behaviour and negatively impacts daily life. Fortunately, the Traditional Chinese Medicine Jia Wei Xiao Yao (JWXY) capsule is effective
Shuhui Zhang +9 more
semanticscholar +1 more source
Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline
The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral ...
Mohammad Akhlaquer Rahman +1 more
doaj +1 more source
Antidepressants versus placebo for depression in primary care [PDF]
Background Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication.
Arroll, Bruce +7 more
core +3 more sources
Potential antidepressant effects of scutellaria baicalensis, hericium erinaceus and rhodiola rosea [PDF]
Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders. Accordingly, bioactive ingredients which are found within a variety of
Biagioni, F +5 more
core +2 more sources

