Results 21 to 30 of about 492,888 (308)

Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides

Frontiers in Immunology, 2023
BackgroundSerum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody fragments ...
Ralph Adams, Callum Joyce, Mikhail Kuravskiy, Katriona Harrison, Katriona Harrison, Zainab Ahdash, Matthew Balmforth, Kelda Chia, Cinzia Marceddu, Matthew Coates, James Snowden, Emmanuel Goursaud, Karelle Ménochet, Jean van den Elsen, Richard J. Payne, Richard J. Payne, Alastair D. G. Lawson, Anthony Scott-Tucker, Alex Macpherson   +18 more
doaj   +1 more source

Lipid-rich bovine serum albumin is beneficial for the early development of bovine embryos, but induces lipid droplet formation in the blastocyst

, 2023
Lipid-rich bovine serum albumin (LR-BSA) has been reported to increase the survival rate of blastocysts after freezing and thawing. However studies on the early development of in vitro fertilised (IVF) embryos are still insufficient in cattle. This study
Lee HakKyo, Kyung-Do Park, Jae-Don Oh, Dae-Jin Kwon   +3 more
core   +1 more source

Grafted block complex coacervate core micelles and their effect on protein adsorption on silica and polystyrene [PDF]

, 2010
peer reviewedWe have studied the formation and the stability of grafted block complex coacervate core micelles (C3Ms) in solution and the influence of grafted block C3M coatings on the adsorption of the proteins beta-lactoglobulin, bovine serum albumin ...
Arie de Keizer, Cohen Stuart, Martien A., Brzozowska, Agata M., Norde, Willem, Christophe Detrembleur, Detrembleur, Christophe, Cohen Stuart, M.A., Agata M. Brzozowska, Willem Norde, de Keizer, Arie, Keizer, A., de, Stuart, Martien Cohen, Norde, W., Brzozowska, A.M., Detrembleur, C., Martien A. Cohen Stuart, de Keizer, A.   +16 more
core   +1 more source

Inlet protein aggregation: a new mechanism for lubricating film formation with model synovial fluids. [PDF]

, 2011
This paper reports a fundamental study of lubricant film formation with model synovial fluid components (proteins) and bovine serum (BS). The objective was to investigate the role of proteins in the lubrication process.
Hart, A, R Underwood, C W Myant, Underwood, R, A Hart, P M Cann, Cann, PM, Fan, J, Myant, CW, J Fan   +9 more
core   +1 more source

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
doaj   +1 more source

New Asymmetric Gemini Triazole Surfactants with a Polar Triethylene Glycol Fragment: Synthesis and Physico-Chemical Properties

Molecules
The present work is devoted to the synthesis and analysis of the physicochemical properties of new functionalized asymmetric Gemini surfactants. Herein, alkyl- and azide-substituted surfactants with symmetric and asymmetric substituents were synthesized ...
Ilshat Bogdanov, Diana Mironova, Elza Sultanova, Vladimir Burilov, Svetlana Solovieva, Igor Antipin   +5 more
doaj   +1 more source

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

Adjuvant properties of polymer based on acrylic acid [PDF]

The Ukrainian Biochemical Journal, 2013
Adjuvant properties of the polymer containing­ acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established.
M. R. Kozak, A. V. Oliynyk, O. S. Zaichenko, V. V. Vlizlo   +3 more
doaj   +1 more source

Translational and rotational motions of albumin sensed by a non-covalent associated porphyrin under physiological and acidic conditions: a fluorescence correlation spectroscopy and time resolved anisotropy study.

, 2008
The interaction between a free-base, anionic water-soluble porphyrin, TSPP, and the drug carrier protein, bovine serum albumin (BSA) has been studied by time-resolved fluorescence anisotropy (TRFA) and fluorescence correlation spectroscopy (FCS) at two ...
Costa, S.M., Hoek, A., van, Borst, J.W., Visser, A.J.W.G., Andrade, S.M.   +4 more
core   +1 more source

Experimental study on effect of dissolved organic matter on mobility of soil colloids

Yantu gongcheng xuebao, 2021
Soil colloids are widely distributed in underground environment. They can facilitate or retard the migration of pollutants in soils, depending on the mobility of the colloids.
ZHANG Wen-jie , JIANG Feng-yong
doaj   +1 more source