Measurement of the Proteinase Inhibitors of the Bovine Pancreas by Radioimmunoassay [PDF]
Bovine pancreas contains two polypeptide trypsin inhibitors that are not homologous and differ in their inhibitory activity towards chymotrypsin, kallikrein, elastase, and other serine proteinases. The Kunitz inhibitor and the Kazal inhibitor are present
Fink, Edwin +2 more
core +1 more source
Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in a Cell Free System from Neurospora crassa [PDF]
Synthesis and transport of mitochondrial proteins were followed in a cell-free homogenate of Neurospora crassa in which mitochondrial translation was inhibited. Proteins synthesized on cytoplasmic ribosomes are transferred into the mitochondrial fraction.
Andrews T. M. +30 more
core +1 more source
Somatostatin receptor imaging: The presence of somatostatin receptors in rheumatoid arthritis [PDF]
Objective. To investigate the in vivo and in vitro expression of somatostatin receptors (SS-R) on synovial membranes of patients with rheumatoid arthritis (RA). Methods.
Krenning, E.P. (Eric) +5 more
core +1 more source
Detection of antibodies to Sendai virus by enzyme-linked immunosorbent assay (ELISA) [PDF]
An enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Sendai virus, a paramyxovirus, is described. The assay was found to be about 20-fold more sensitive than the hemagglutination inhibition assay.
Avrameas +17 more
core +1 more source
Synthesis and biodistribution of immunoconjugates of a human IgM and polymeric drug carriers [PDF]
The synthesis and purification of radiolabelled immunoconjugates, composed of a human IgM monoclonal antibody directed against an intracellular tumour-associated antigen and either poly (alpha-L-glutamic acid) (PGA) or poly[N5-(2-hydroxyethyl)-L ...
Anderson, James M. +9 more
core +2 more sources
Synthesis and evaluation of a radioiodinated tracer with specificity for poly(ADP-ribose) polymerase-1 (PARP-1) in vivo [PDF]
Interest in nuclear imaging of poly(ADP-ribose) polymerase-1 (PARP-1) has grown in recent years due to the ability of PARP-1 to act as a biomarker for glioblastoma and increased clinical use of PARP-1 inhibitors.
Blair, Adele +6 more
core +3 more sources
Protein phosphorylation in yeast mitochondria [PDF]
We describe the identification and submitochondrial localization of four protein kinases and of their target proteins in derepressed yeast mitochondria. The activity of one of the kinases depends on the presence of cyclic AMP (cAMP).
Ashwell +37 more
core +2 more sources
Radioiodinated somatostatin analogue RC-160: preparation, biological activity, in vivo application in rats and comparison with [123I-Tyr3]octreotide [PDF]
We have evaluated the potential usefulness of the radioiodinated octapeptide RC-160, a somatostatin analogue, which might serve as a radiopharmaceutical for the in vivo detection of somatostatin receptor-positive tumours. For this purpose, iodine-123 and
Bakker, W.H. (Willem) +10 more
core +1 more source
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Normal Response Curve to Exercise of Relative Cardiac Output Measured with Radioiodinated Serum Albumin [PDF]
A simple, relatively precise, and clinically applicable indirect method of determining relative cardiac output is presented. The principle involved is a modification of the dye-dilution principle and is performed by external monitoring of intravenously injected radioiodinated serum albumin combined with a standard detecting and recording device.
S L, WEINBERG +4 more
openaire +2 more sources

