Results 11 to 20 of about 3,029 (167)

The Silver Jubilee (2025) of Insulin Glargine: Introducing the Era of Long-Acting Insulin Analogues for Diabetes Mellitus. [PDF]

Diabetes Obes Metab
ABSTRACT In the year 2000 the first once daily long‐acting bioengineered insulin analogue (LAIA), insulin glargine (‘glargine’), a true basal insulin (BI), became available for clinical use. This led to the decline in the 50‐year‐old era and prominence of the intermediate‐acting insulins, neutral protamine Hagedorn (NPH) and lente, requiring twice ...
Bolli GB, Home PD, Lepore M, Riddle MC, Porcellati F, Fanelli CG, Lucidi P, Yki-Järvinen H, Becker RH, Owens DR.   +9 more
europepmc   +2 more sources

Homogeneous tumor targeting with a single dose of HER2-targeted albumin-binding domain-fused nanobody-drug conjugates results in long-lasting tumor remission in mice [PDF]

, 2021
Background: The non-homogenous distribution of antibody-drug conjugates (ADCs) within solid tumors is a major limiting factor for their wide clinical application. Nanobodies have been shown to rapidly penetrate into xenografts, achieving more homogeneous
Muns, Joey A, Adamzek, Kevin, Xenaki, Katerina T, Dorrestijn, Bram, Oliveira, Sabrina, Houthoff, HendrikJan, Doulkeridou, Sofia, van Bergen En Henegouwen, Paul Mp   +7 more
core   +2 more sources

DISTRIBUTION IN THE RAT OF PARTIALLY DENATURED IODINATED SERUM ALBUMIN

, 1964
The distribution of heated radioiodinated human serum albumin (IHSA) was investigated in the rat.Increase in duration of heat treatment at 70 °C resulted in increased liver uptake.
Monte Blau, Robert F. Manske
core   +1 more source

Alterations of Serum Biochemical and Urinary Parameters in a Canine Population before and after Intravenous Contrast Administration [PDF]

, 2021
Intravenous iodinated contrast (IVIC) medium is routinely administered to dogs. Scattered information exists regarding the serum biochemical or urinary profiles associated with the administration of IVIC in dogs.
Claudio Bellino, Gianella, P., Roncone, S., Miniscalco, B., Paola Gianella, Bellino, C., Barbara Bruno, Cagnasso, F., Valazza, A., Renato Zanatta, Antonio Borrelli, Bruno, B., Borrelli, A., Zanatta, R., Alberto Valazza, Federica Cagnasso, Barbara Miniscalco, Silvia Roncone, Ilaria Lippi   +18 more
core   +2 more sources

Use of Microwave Radiometry to Monitor Thermal Denaturation of Albumin [PDF]

, 2018
This study monitored thermal denaturation of albumin using microwave radiometry. Brightness Temperature, derived from Microwave Emission (BTME) of an aqueous solution of bovine serum albumin (0.1 mM) was monitored in the microwave frequency range 3.8–4.2
Galiullin, Rafael A., Yuri Ivanov, Vadim Y., Tatur, Vadim S. Ziborov, Nina D., Ivanova, Yuri, Ivanov, Rafael A. Galiullin, Vadim S., Ziborov, Sergey G., Vesnin, Rafael A., Galiullin, Andrey F., Kozlov, Ivanov, Yuri, Kozlov, Andrey F., Igor, Goryanin, Vadim Y. Tatur, Ziborov, Vadim S., Ivanova, Nina D., Vesnin, Sergey G., Igor Goryanin, Andrey F. Kozlov, Tatur, Vadim Y., Tatyana O. Pleshakova, Goryanin, Igor, Pleshakova, Tatyana O., Sergey G. Vesnin, Tatyana O., Pleshakova, Goryanin, Igor; id_orcid, Nina D. Ivanova   +27 more
core   +1 more source

Long-Circulating Iodinated Albumin–Gadolinium Nanoparticles as Enhanced Magnetic Resonance and Computed Tomography Imaging Probes for Osteosarcoma Visualization

, 2015
Multimodal imaging probes represent an extraordinary tool for accurate diagnosis of diseases due to the complementary advantages of multiple imaging modalities.
Zhuoyan Ling (1615195), Yangyun Wang (1544839), Qianliang Wang (1615192), Yujing Liu (389417), Guodong Liu (278986), Ling Lv (1615189), Liubing Li (1614292), Jun Yan (28467), Yong Wang (12837), Liqin Shen (1614298)   +9 more
core   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Experimental in situ measurement of concentration polarisation during ultra- and micro-filtration of bovine serum albumin and Dextran Blue solutions

, 2022
S.51-63Concentration polarisation arising during the filtration of bovine serum albumin (BSA) and Dextran Blue is studied by two non-intrusive techniques.
McDonogh, R.M., Bauser, H., Stroh, N., Grauschopf, U.   +3 more
core   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Synthesis and characterization of an iodinated bile-salt derivative for photoaffinity-labeling

, 1984
The synthesis and characterisation of a novel iodinated bile salt derivative, 125I-labelled 3ß-azidocholylhistamine, is described. The derivative is handled by rat liver in a similar manner to taurocholate and binding to bovine serum albumin, a well ...
Percy-Robb, Ian W., Henderson, Colin J.
core   +1 more source