Results 21 to 30 of about 5,390 (169)
The hepatic clearance of recombinant tissue-type plasminogen activator decreases after an inflammatory stimulus [PDF]
, 2000 We have shown that tissue-type plasminogen activator (tPA) and plasma kallikrein share a common pathway for liver clearance and that the hepatic clearance rate of plasma kallikrein increases during the acute-phase (AP) response.
Borges, Durval Rosa +2 more
core +4 more sources
Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Advanced Healthcare Materials, EarlyView.Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee +10 more
wiley +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Differential interaction of glimepiride and glibenclamide with the β-cell sulfonylurea receptor II [PDF]
, 1994 Glimepiride is a novel sulfonylurea for the treatment of type II-diabetic patients exhibiting different receptor binding kinetics to β-cell membranes with 8–9-fold higher koff rate and 2.5–3-fold higher kon rate compared to glibenclamide (see ...
Aguilar-Bryan +29 more
core +1 more source
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
Advanced Materials, EarlyView.This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source
Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics
Advanced Electronic Materials, EarlyView.Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim +7 more
wiley +1 more source
Blood Volume in Relation to Body Weight of the Male Rat Using Radio-Iodinated Serum Albumin.
Experimental Biology and Medicine, 1965 SummaryTotal blood volume was determined in 122 male rats using RISA. The values were related to body weight and a least squares regression line was plotted. This regression line enables one to predict total blood volume for any given body weight. The method utilizing RISA and whole blood counting has the advantage of simplicity with minimal loss of ...
A P, ORMOND, J M, RIVERA-VELEZ
openaire +2 more sources
Binding of radio-iodinated gonadotropin to the ovary of exotic carp (Cyprinus carpio Lin.) [PDF]
, 2000 Heterologous murrel gonadotropic hormone (m-GtH) binds to common carp oocyte plasma membrane and enhances steroid secretion. With increasing concentration of radio-labelled hormone the receptor binding is also found to increase linearly up to a certain ...
Bhattacharya, S., Chakraborty, B.
core
Transport and equilibrium uptake of a peptide inhibitor of PACE4 into articular cartilage is dominated by electrostatic interactions [PDF]
, 2010 The availability of therapeutic molecules to targets within cartilage depends on transport through the avascular matrix. We studied equilibrium partitioning and non-equilibrium transport into cartilage of Pf-pep, a 760 Da positively charged peptide ...
Byun, Sangwon +5 more
core +1 more source