Results 91 to 100 of about 313,077 (257)

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu   +9 more
wiley   +1 more source

Preoperative Serum Alkaline Phosphatase and Neurological Outcome of Cerebrovascular Surgery. [PDF]

J Clin Med, 2022
Park S, Choi ES, Jung HW, Lee JY, Park JW, Bang JS, Jeon YT.   +6 more
europepmc   +1 more source

Assessment of Requirement of Routine Intraoperative Cholaniography at Cholecystectomy [PDF]

, 2013
Introduction: Retained choledochal stones are classified as the stones that were left at the time of surgery or diagnosed shortly after the cholecystectomy. Choledochal stones may be silent and often are discovered incidentally.
Alavi-farzane, Babak., Khoshnood, Asghar., Shiryazdi, Seyed Mostafa.   +2 more
core   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source

High-dose vitamin D supplementation is related to an improvement in serum alkaline phosphatase in COVID-19 patients; a randomized double-blinded clinical trial. [PDF]

J Health Popul Nutr, 2023
Moghaddam RR, Khorasanchi Z, Noor AR, Moghadam MSF, Esfahani AJ, Alyakobi AKM, Alboresha ML, Sharifan P, Bahari A, Rezvani R, Aghasizade M, Heshmati M, Darban RA, Ferns G, Mobarhan MG.   +14 more
europepmc   +1 more source

GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation

Advanced Science, EarlyView.
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim, Quan Pan, Zeyu Liu, Weiqi Ai, Hye Won Han, Sakhila K. Banu, Robert Y.L. Tsai, Gus A. Wright, Shaodong Guo, Yuxiang Sun   +9 more
wiley   +1 more source

Serum Alkaline Phosphatase in Cryptogenic Stroke Cases with Active Cancer. [PDF]

Intern Med, 2022
Izumi T, Nanaura H, Iguchi N, Ozaki M, Sugie K.   +4 more
europepmc   +1 more source

Salivary inflammatory biomarkers during initial orthodontic tooth movement [PDF]

, 2016
BACKGROUND: Orthodontic tooth movement is a complex process involving a number of inflammatory and anabolic/catabolic pathways. Further, successful treatment depends on proper timing of orthodontic measures with regard to patient’s growth spurt ...
Serrenho, Ana
core   +1 more source

Ultrasound‐Responsive Piezoelectric Membrane Promotes Osteoporotic Bone Regeneration via the “Two‐Way Regulation” Bone Homeostasis Strategy

Advanced Science, EarlyView.
Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu, Tianlong Wang, Jinhui Zhao, Lei Zhang, Zhiqing Liu, Yixing Chen, Yiping Luo, Yaqi Liu, Yan Chen, Hui Jiang, Dilixiati Duolikun, Junjian Liu, Wentao Cao, Longpo Zheng   +13 more
wiley   +1 more source

Pretreatment levels of serum alkaline phosphatase are associated with the prognosis of patients with non‑small cell lung cancer receiving immune checkpoint inhibitors. [PDF]

Oncol Lett, 2023
Yang T, Cheng J, Fu S, Sun T, Yang K, You J, Li F.   +6 more
europepmc   +1 more source