Results 81 to 90 of about 1,546,756 (303)

Mixed function oxidation and enzymes: kinetic and structural properties of an oxidatively modified alkaline phosphatase

, 1988
No major structural alteration of alkaline phosphatase can be observed in the early stages of enzyme oxidative inactivation by the ascorbate model system.
Mordente, Alvaro, Meucci, Elisabetta
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Serial Measurements of Serum Alkaline Phosphatase for Early Prediction of Osteopaenia in Preterm Infants

, 2012
AIM: Osteopaenia commonly occurs in preterm infants; however , its diagnosis is often delayed when based on radiological findings. The aim of this study was to examine whether serial measurements of bone turnover markers are useful for early prediction ...
HUNG, YI-LI;CHEN, PAU-CHUNG;JENG, SUH-FANG;HSIEH, CHIA-JUNG;PENG, STEVEN SHINN-FORNG;YEN, RUOH- FANG;CHOU, HUNG-CHIEH;CHEN, CHIEN-YI;TSAO, PO- NIEN;HSIEH, WU-SHIUN, 洪依利;陳保中;鄭素芳;謝佳容;彭信逢;顏若芳;周弘傑;陳倩儀;曹伯年;謝武勳   +1 more
core  

Associations of albuminuria among serum alkaline phosphatase quartiles in participants with eGFR ≥ 60 ml/min/1.73m².

, 2015
Associations of albuminuria among serum alkaline phosphatase quartiles in participants with eGFR ≥ 60 ml/min/1.73m2.
Sang Youb Han (407598), Se Won Oh (509965), Kum Hyun Han (407599)   +2 more
core   +1 more source

Prevalence of Vitamin D Deficiency Among Children (0-12 Years) in Secondary Care Hospital: A Cross-Sectional Study Over One Year Period

Journal of Pharmacy and Bioallied Sciences
Objective: This study was carried out to assess the prevalence of vitamin D deficiency and insufficiency in study group of children aged 0 to 12 years.
Yousef Alrohaimi, Badar A Almuqhem
doaj   +1 more source

A comparative study of phosphate binders in patients with end stage kidney disease undergoing hemodialysis

Saudi Journal of Kidney Diseases and Transplantation, 2014
In the present study, a comparative evaluation of the effects of calcium acetate, calcium carbonate, sevelamer hydrochloride and lanthanum carbonate was carried out in 120 patients with end stage kidney disease (ESKD) undergoing hemodialysis. Biochemical
Viken A Prajapati, Varsha J Galani, Pankaj R Shah   +2 more
doaj   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Associations between serum alkaline phosphatase quartiles and metabolic syndrome according to the estimated glomerular filtration rate (eGFR).

, 2015
*The odds ratios of serum alkaline phosphatase quartiles were adjusted by age, sex, hemoglobin, cholesterol, current smoking, alcohol use, hypertension, myocardial infarction, stroke, and malignancy.Associations between serum alkaline phosphatase ...
Sang Youb Han (407598), Se Won Oh (509965), Kum Hyun Han (407599)   +2 more
core   +1 more source

Comparison of serum calcium, magnesium, phosphate, alkaline phosphatase, and vitamin D levels in children consuming reverse osmosis, non reverse osmosis, and high fluoride drinking water

Scientific Reports
Water is vital for the human body. Due to concerns over tap water, preference for taste, and convenience, there has been increased consumption of reverse osmosis (RO) water.
H. M. Thippeswamy , Raghavendra Shanbhog, M. Nanditha Kumar, S. N. Prashanth, P. Smitha   +4 more
doaj   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source