Results 61 to 70 of about 234,032 (301)

Serum biochemical evaluation of healing of critical-sized long bone defects in rats treated with biphasic hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) bioceramic scaffolds

Journal of Veterinary and Animal Sciences
Critical-sized long bone defects are those that would not heal spontaneously despite surgical stabilisation. The use of bioceramic scaffold has shown promising results in the repair of bone defects.
Ashok R. Unni, Syam K. Venugopal, K. D. John Martin, S. Anoop , S. Maya Maya, B. Dhanush Krishna   +5 more
doaj   +1 more source

The Effect of Insulin induced Hypoglycemia on ketoconazole Hepatototxicity in Rabbit [PDF]

The Medical Journal of Basrah University, 2015
Background: Hypoglycemia is one of the most common side effect of insulin treatment, it affect liver and can potentiate ketoconazole toxicity. Objectives: To measure effect of ketoconazole on liver enzymes, hypoglycemic oxidative stress and to evaluate
Nabeel A.J.Ali, Riyad H. Zayer Anaed
doaj   +1 more source

Evaluation of Serum Zinc Status and Serum Alkaline Phosphatase Activity in Alcoholic Liver Disease [PDF]

, 2016
BACKGROUND : Alcohol remains to be the major cause of morbidity and mortality worldwide. Undoubtfully it is a hepatotoxic compound leading to spectrum of ethanol related liver damage.
Uma, T
core  

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Biochemical Features of Alcohol-Induced Liver Disease in Native Versus Non-Native Canadians

Canadian Journal of Gastroenterology, 1990
The medical records of 37 native and 40 non-native adult Canadians with alcohol-induced liver disease were reviewed in order to determine whether a biochemical pattern of bile ductular injury (increase in serum alkaline phosphatase levels) was more ...
GY Minuk, W Thompson
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Biochemical markers of bone turnover in the diagnosis of renal osteodystrophy in dialyzed children

The Turkish Journal of Pediatrics, 2004
In this study we investigated the value of biochemical markers of bone turnover in the diagnosis of renal osteodystrophy in dialysis patients. The study was carried out in 22 chronic renal failure patients (mean age: 16.1 +/- 4.5) being treated ...
Esra Baskin, Nesrin Beşbaş, Umit Saatçi, Gülşen Hasçelik, Rezan Topaloğlu, Seza Ozen, Ayşin Bakkaloğlu   +6 more
doaj  

Expression analysis of zinc-metabolizing enzymes in the saliva as a new method of evaluating zinc content in the body: two case reports and a review of the literature

Journal of Medical Case Reports
Background The activity level of alkaline phosphatase, a zinc-requiring enzyme in the serum, is used to indicate zinc nutritional status; however, it does not correlate with serum zinc levels or subjective symptoms of taste disorder in many cases. Hence,
Ken-ichiro Sakata, Ayako Hashimoto, Taiho Kambe, Jun Sato, Noritaka Ohga, Yutaka Yamazaki, Masahide Koyachi, Itagaki Tatsuki, Mai Okada, Okura Taro, Hiroshi Hikasa, Yoshimasa Kitagawa   +11 more
doaj   +1 more source

EFFECTS OF NORFLOXACIN (NOROXIN) AND OFLAXACIN (TARIVID) ON LIVER AND KIDNEY FUNCTIONS AND SOME OTHER PARAMETERS OF ADULT MALE RATS

Zagazig Journal of Pharmaceutical Sciences, 1997
The effect of noroxin and tarivid on liver and kideny functions, total lipids, blood glucose and some minerals was studied. After one week treatment tarivid significantly increasesd serum glutamic oxaloacetic transferase (SGOT), total bilirubin, alkaline
Mervat E. Askar, Fatma R. Abdalla , Rawia S. Amin   +2 more
doaj   +1 more source