Results 61 to 70 of about 339,635 (344)

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory   +3 more
wiley   +1 more source

Efficacy of pleural fluid alkaline phosphatase and its ratio to serum levels in distinguishing exudates from transudates

open access: yesLung India, 2004
The objective of present study was to evaluate the efficacy of pleural fluid alkaline phosphatase and its ratio to serum levels to classify pleural fluids. A total of 80 patients were divided in transudates and exudates on the basis of extensive clinical,
Gupta K   +4 more
doaj  

Biochemical Features of Alcohol-Induced Liver Disease in Native Versus Non-Native Canadians

open access: yesCanadian Journal of Gastroenterology, 1990
The medical records of 37 native and 40 non-native adult Canadians with alcohol-induced liver disease were reviewed in order to determine whether a biochemical pattern of bile ductular injury (increase in serum alkaline phosphatase levels) was more ...
GY Minuk, W Thompson
doaj   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]

open access: yes, 2007
We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T   +5 more
core  

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

open access: yesAdvanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery   +10 more
wiley   +1 more source

Biochemical markers of bone turnover in the diagnosis of renal osteodystrophy in dialyzed children

open access: yesThe Turkish Journal of Pediatrics, 2004
In this study we investigated the value of biochemical markers of bone turnover in the diagnosis of renal osteodystrophy in dialysis patients. The study was carried out in 22 chronic renal failure patients (mean age: 16.1 +/- 4.5) being treated ...
Esra Baskin   +6 more
doaj  

Expression analysis of zinc-metabolizing enzymes in the saliva as a new method of evaluating zinc content in the body: two case reports and a review of the literature

open access: yesJournal of Medical Case Reports
Background The activity level of alkaline phosphatase, a zinc-requiring enzyme in the serum, is used to indicate zinc nutritional status; however, it does not correlate with serum zinc levels or subjective symptoms of taste disorder in many cases. Hence,
Ken-ichiro Sakata   +11 more
doaj   +1 more source

Evaluation of bone health among epileptic patients using biochemical markers and DEXA scan: an Egyptian study

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018
Background An association between antiepileptic drugs, low bone mineral density (BMD), fractures, and abnormalities in bone metabolism has been suggested for a longer period, although conclusive evidence has not been reported.
Ebtesam Mohamed Fahmy   +4 more
doaj   +1 more source

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