Results 91 to 100 of about 1,546,756 (303)

Comparison of CA 125 and Placental Alkaline Phosphatase as Ovarian Tumor Markers

open access: yes, 1987
The serum concentrations of CA 125 and placental alkaline phosphatase were analyzed in 16 patients with ovarian cancer. Increased serum levels of CA 125 and placental alkaline phosphatase were observed in 75% and 50% of the cancer patients, respectively.
Olli-Pekka Kallioniemi   +2 more
core   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Serum Levels of Alkaline Phosphatase Isozymes in Gynecologic Malignancies

open access: yes, 2009
To study the serum level of placental alkaline phosphatase activities in women with gynecologic malignancies, isoelectric focusing (IEF) technique was employed to differentiate isozymes of alkaline phosphatase (ALP).
CHENG, NAI-CHEN;HUANG, CHIEN-CHU;CHEN, RUEY-JIEN;HSIEH, CHANG-YAO;CHOW, SONG-NAN   +1 more
core  

Correlation between serum levels of uric acid with bone turnover markers in postmenopausal women

open access: yesIranian South Medical Journal, 2015
Background: There is accumulation evidence regarding the protective role of higher serum uric acid in bone loss and osteoprotic fractures. This effect may arise from its antioxidant properties.
Fariba Karimi   +8 more
doaj  

Sample storage and fasting times affect blood serum and plasma components in fasted and non-fasted broiler chickens

open access: yesJournal of Applied Poultry Research
Summary: We determined the impacts of blood fraction, fasting and samples storage times on the total protein, albumin, globulin, uric acid, creatinine concentrations, and alkaline phosphatase activity in 70 45-d-old male Cobb 500® broiler chickens. Blood
Clauber Polese   +12 more
doaj   +1 more source

Multiple fractures, pain, and severe disability in a patient with adult-onset hypophosphatasia

open access: yesBone Reports, 2016
Hypophosphatasia (HPP) is a rare, inherited metabolic bone disease resulting from mutations in the gene encoding tissue non-specific alkaline phosphatase.
Neil A. Braunstein
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

Agarose gel electrophoresis of alkaline phosphatase isoenzymes in the serum of hyperthyroid cats

open access: yes
Cats with hyperthyroidism [(increased serum thyroxine (T(4))] commonly have increased serum alkaline phosphatase (ALP) activity in addition to other serum biochemical abnormalities. Serum biochemical profiles were obtained from 10 hyperthyroid cats which

core   +1 more source

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