This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang +3 more
wiley +1 more source
Serum alkaline phosphatase is a strong predictor of mortality in ESKD patients: analysis of the RISCAVID cohort. [PDF]
Panichi V +5 more
europepmc +1 more source
Non-Linear Association Between Serum Alkaline Phosphatase and 3-Month Outcomes in Patients With Acute Stroke: Results From the Xi'an Stroke Registry Study of China. [PDF]
Guo W +9 more
europepmc +1 more source
Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou +16 more
wiley +1 more source
Estimation and Correlation of Serum Albumin and Serum Alkaline Phosphatase Levels Between Smokers and Non-smokers With Generalized Chronic Periodontitis. [PDF]
Lalkota H +4 more
europepmc +1 more source
Incidence of Marek’s Disease as Related to Phenotypes of Serum Alkaline Phosphatase
A.A. GRUNDER +3 more
openalex +1 more source
In vivo and in vitro Studies of Kinetic Changes of Serum, Liver and Brain High and Low Molecular Weight Alkaline Phosphatase Following Aluminium Exposure in Rat [PDF]
Seyyed Mehdi Mirh +3 more
openalex +1 more source
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li +17 more
wiley +1 more source
Moderate-severe aortic arch calcification and high serum alkaline phosphatase co-modify the risk of cardiovascular events and mortality among chronic hemodialysis patients. [PDF]
Chang CH, Liou HH, Wu CK.
europepmc +1 more source

