Results 51 to 60 of about 15,590 (176)

Study of Correlation of Serum Cholinesterase Level with Peradeniya Organophosphorus Poisoning Scale in Organophosphorus Poisoning

open access: yesJournal of Karnali Academy of Health Sciences, 2022
Background- Organophosphorus compound poisoning is a common problem in Nepal. In rural areas, cholinesterase levels are not readily available and other clinical severity scores would be useful.
Dhiraj Gurung
doaj  

Dynamic SPECT Assessment of Hepatic Function in Patients With Liver Disease: A Systematic Review and Meta‐Analysis

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Dynamic Single Photon Emission Computed Tomography (dynSPECT) is an advanced functional imaging modality that enables estimation of temporal changes in radiopharmaceutical distribution and physiological function. While dynSPECT has been employed in several clinical applications, it has not been widely applied to liver imaging ...
Bader Aloufi   +3 more
wiley   +1 more source

Correlation between Cholinesterase and Paraoxonase 1 Activities: Case Series of Pesticide Poisoning Subjects

open access: yesBioImpacts, 2013
Introduction: Acute exposure to pesticide due to suicidal poisoning is the most extensive cause of pesticide exposure, compared with all other causes including agricultural or industrial exposure.
S Austin Richard   +2 more
doaj   +1 more source

Association Between Locomotive Syndrome and Metabolic Dysfunction‐Associated Steatotic Liver Disease in a Health Examination Cohort: A Cross‐Sectional Study

open access: yesHepatology Research, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is associated with liver fat and other health problems. In this study of 7776 adults who underwent health examinations, early mobility impairment was more common in individuals with MASLD.
Shinya Yokoyama   +11 more
wiley   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

open access: yesLegume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid   +4 more
wiley   +1 more source

Effect of Gallic Acid on Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Diazinon in Vitro and in Vivo

open access: yesJournal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Diazinon is an organophosphate insecticide that binds to the acetylcholinesterase enzyme after metabolization causing its inactivation. Galic acid is a polyphenolic compound with nucleophilic properties.
Farzaneh Sadat Motafeghi   +3 more
doaj  

Serum Cholinesterase Levels in Patients with Cancer

open access: yesAnesthesia & Analgesia, 1979
Serum cholinesterase levels were determined in 180 patients with carcinoma and in 146 normal subjects. Serum cholinesterase activity was significantly lower in patients suffering from cancer than in normal controls, though still within the normal range.
Kaniaris, P.   +3 more
openaire   +3 more sources

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal   +10 more
wiley   +1 more source

Discovery of a Potent and Selective MAO‐B Inhibitor From a Donepezil‐Linked Chalcone Library With Promising Antiparkinsonian Activity

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A focused library of 19 donepezil‐linked chalcones (DLCs) was efficiently synthesised through microwave‐assisted Claisen‐Schmidt condensation and subsequently profiled for their inhibitory activities against cholinesterases (AChE and BuChE) as well as monoamine oxidases (MAO‐A and MAO‐B).
Azize Kirac‐Aydin   +11 more
wiley   +1 more source

Investigating the Antidiabetic Effects of Calotropis procera: Preclinical Assessment

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Calotropis Procera In vitro/Diabetic rodent model Improved β‐cell function, reduced hepatic gluconeogenesis antioxidant activity. ABSTRACT Diabetes mellitus (DM) is a metabolic disease characterized by persistent hyperglycemia, oxidative stress, and inflammation, often leading to severe complications.
Yu‐Cheng Kuo   +10 more
wiley   +1 more source

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