Results 291 to 300 of about 2,079,920 (381)

The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review

open access: yesImmunology, EarlyView.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source

Serum ferritin and the risk of early-onset colorectal cancer. [PDF]

open access: yesWorld J Gastrointest Oncol
Urback AL   +7 more
europepmc   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

open access: yesImmunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho   +3 more
wiley   +1 more source

METTL3/YTHDF3 m6A axis promotes ferroptosis in diabetic kidney disease by stabilizing TfR1

open access: yesJournal of Diabetes Investigation, EarlyView.
METTL3/YTHDF3 m6A axis promoted ferroptosis in DKD by stabilizing TfR1, which could provide a reference for DKD treatment. ABSTRACT Objective Diabetic kidney disease (DKD) is a common complication of diabetes. N6‐Methyladenosine (m6A) modification is a widely studied epigenetic mechanism.
Jinmei Zhang   +5 more
wiley   +1 more source

Regulatory role of ATF2 in trophoblast ferroptosis via the PI3K/Akt/Nrf2 pathway in gestational diabetes mellitus

open access: yesJournal of Diabetes Investigation, EarlyView.
ATF2 is highly expressed in GDM placental tissues and promotes ferroptosis in trophoblast cells by inhibiting the PI3K/Akt/Nrf2 pathway, thereby affecting trophoblast function and GDM progression. ABSTRACT Aims/Introduction To investigate the expression of ATF2 in GDM patients and its impact on trophoblast viability and ferroptosis, as well as to ...
Dandan Xia   +3 more
wiley   +1 more source

Diagnostic electron microscopy in human infectious diseases – Methods and applications

open access: yesJournal of Microscopy, EarlyView.
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley   +1 more source

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