Results 101 to 110 of about 135,067 (303)

Magnesium deficiency and increased inflammation: current perspectives

open access: yes, 2018
Forrest H Nielsen Research Nutritionist Consultant, Grand Forks, ND, USA Abstract: Animal studies have shown that magnesium deficiency induces an inflammatory response that results in leukocyte and macrophage activation, release of inflammatory cytokines
Nielsen FH, Forrest H Nielsen
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

A STUDY OF SERUM MAGNESIUM AND CALCIUM LEVELS IN MISSED ABORTION

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background:Pregnancy is considered as a physiological stress, normal static metabolism of a woman is changed into dynamic anabolism, calcium (Ca) is the first most abundant cation in the human body, whereas magnesium (Mg) is the fourth most abundant one,
Abdulrazak H Alnakash   +3 more
doaj   +4 more sources

Hypomagnesemia in short bowel syndrome patients

open access: yesSão Paulo Medical Journal, 2000
CONTEXT: Magnesium support to small bowel resection patients. OBJECTIVE: Incidence and treatment of hypomagnesemia in patients with extensive small bowel resection. DESIGN: Retrospective study.
Simone Chaves Miranda   +3 more
doaj   +1 more source

Effect of transdermal magnesium cream on serum and urinary magnesium levels in humans: A pilot study. [PDF]

open access: yes, 2017
Oral magnesium supplementation is commonly used to support a low magnesium diet. This investigation set out to determine whether magnesium in a cream could be absorbed transdermally in humans to improve magnesium status.In this single blind, parallel ...
Andrea Rosanoff   +11 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Correlation between serum magnesium level and arteriosclerosis in maintenance hemodialysis patients

open access: yesLinchuang shenzangbing zazhi
Objective To explore the effect of serum magnesium level on arteriosclerosis in maintenance hemodialysis(MHD) patients. Methods From January 1, 2020 to June 30, 2023, 155 MHD patients were recruited.
Dan-yan Min   +6 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Protein Binding States of Zinc, Cadmium and Magnesium in Serum of Coho Salmon (Oncorhynchus kisutch)

open access: yes, 1987
Protein binding states of zinc, cadmium and magnesium in serum of coho salmon (Oncorhynchus kisutch) were studied in vitro. In the non-treated serum, the major zinc-binding protein was detected in the third fraction of the elution profile by 280 nm ...
熊田, 弘   +12 more
core  

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