Results 11 to 20 of about 124,117 (258)

Prediction of serum HIV-1 neutralization titers of VRC01 in HIV-uninfected Antibody Mediated Prevention (AMP) trial participants

Human Vaccines & Immunotherapeutics, 2022
VRC01 is being evaluated in the AMP efficacy trials, the first assessment of a passively administered broadly neutralizing monoclonal antibody (bnAb) for HIV-1 prevention.
Yunda Huang, Lily Zhang, Amanda Eaton, Nonhlanhla N. Mkhize, Lindsay N. Carpp, Erika Rudnicki, Allan DeCamp, Michal Juraska, April Randhawa, Adrian McDermott, Julie Ledgerwood, Philip Andrew, Shelly Karuna, Srilatha Edupuganti, Nyaradzo Mgodi, Myron Cohen, Lawrence Corey, John Mascola, Peter B. Gilbert, Lynn Morris, David C. Montefiori   +20 more
doaj   +1 more source

A rapid real-time polymerase chain reaction-based live virus microneutralization assay for detection of neutralizing antibodies against SARS-CoV-2 in blood/serum.

PLoS ONE, 2021
BackgroundIndividuals recovering from COVID-19 are known to have antibodies against the Spike and other structural proteins. Antibodies against Spike have been shown to display viral neutralization.
Syed Hani Abidi, Kehkashan Imtiaz, Akbar Kanji, Shama Qaiser, Erum Khan, Kiran Iqbal, Marc Veldhoen, Kulsoom Ghias, J Pedro Simas, Zahra Hasan   +9 more
doaj   +3 more sources

Neutralization of Dengue Virus Serotypes by Sera from Dengue-Infected Individuals Is Preferentially Directed to Heterologous Serotypes and Not against the Autologous Serotype Present in Acute Infection

Viruses, 2021
Sequential infections of humans by the four different dengue serotypes (DENV-1–4) lead to neutralizing antibodies with group, cross, and type specificity.
Heidi Auerswald, Simone Kann, Leonard Klepsch, Janne Hülsemann, Ines Rudnik, Sebastian Schreiber, Philippe Buchy, Michael Schreiber   +7 more
doaj   +1 more source

Genetic Characterization of Feline Parvovirus Isolate Fe–P2 in Korean Cat and Serological Evidence on Its Infection in Wild Leopard Cat and Asian Badger

Frontiers in Veterinary Science, 2021
Feline parvovirus (FPV) is a small, non-enveloped, single-stranded DNA virus that infects cats. We recently isolated a feline parvovirus Fe–P2 strain from a dead stray cat in Iksan, 2017.
Young Ji Kim, Young Ji Kim, Sun-Woo Yoon, Sun-Woo Yoon, Jin Ho Jang, Jin Ho Jang, Dae Gwin Jeong, Dae Gwin Jeong, Beom Jun Lee, Hye Kwon Kim   +9 more
doaj   +1 more source

Different Neutralization Sensitivity of SARS-CoV-2 Cell-to-Cell and Cell-Free Modes of Infection to Convalescent Sera

Viruses, 2021
The COVID-19 pandemic caused by SARS-CoV-2 has posed a global threat to human lives and economics. One of the best ways to determine protection against the infection is to quantify the neutralizing activity of serum antibodies.
Natalia Kruglova, Andrei Siniavin, Vladimir Gushchin, Dmitriy Mazurov   +3 more
doaj   +1 more source

An AGM model for changes in complement during pregnancy: neutralization of influenza virus by serum is diminished in late third trimester. [PDF]

PLoS ONE, 2014
Pregnant women in the third trimester are at increased risk of severe influenza disease relative to the general population, though mechanisms behind this are not completely understood. The immune response to influenza infection employs both complement (C'
Anne E Mayer, Griffith D Parks
doaj   +1 more source

NEUTRALIZATION OF INFLUENZA A VIRUS BY HUMAN SERUM [PDF]

Journal of Experimental Medicine, 1941
A linear relationship exists between the quantity of human serum used and the quantity of influenza A virus neutralized. By means of this relationship it is possible to determine the maximum quantity of virus which a given human serum can neutralize. This quantity, the neutralizing capacity, is a fixed value and, unlike the serum dilution end point, is
F L, Horsfall, E H, Lennette
openaire   +2 more sources

Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]

PLoS ONE, 2015
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates, Victoria Olson, Scott Smith, Nishi Patel, Inger Damon, Kevin Karem   +5 more
doaj   +1 more source

Development and Evaluation of an Enzyme-Linked Immunosorbent Assay Targeting Rabies-Specific IgM and IgG in Human Sera

Viruses, 2023
Immunity from rabies depends on rabies virus neutralizing antibodies (RVNA) induced after immunization; however, the influence of antibody isotype switching has not been extensively investigated.
Michelle D. Zajac, Maria Teresa Ortega, Susan M. Moore   +2 more
doaj   +1 more source

Multiple Assessment and Serum Neutralization of Arbovirus Mixtures [PDF]

Applied Microbiology, 1970
Mixtures of Venezuelan equine encephalomyelitis, Rift Valley fever, and chikungunya viruses may be assayed by selective immunofluorescence staining of infected cell monolayers. A multiple serum neutralization test is described for quantifying reactions of these viruses with mixtures of serum antibodies.
N, Hahon, C J, Mayhew
openaire   +2 more sources