Results 21 to 30 of about 124,117 (258)

Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets

mBio, 2020
Due to the urgent need of a therapeutic treatment for coronavirus (CoV) disease 2019 (COVID-19) patients, a number of FDA-approved/repurposed drugs have been suggested as antiviral candidates at clinics, without sufficient information. Furthermore, there
Su-Jin Park, Kwang-Min Yu, Young-Il Kim, Se-Mi Kim, Eun-Ha Kim, Seong-Gyu Kim, Eun Ji Kim, Mark Anthony B. Casel, Rare Rollon, Seung-Gyu Jang, Min-Hyeok Lee, Jae-Hyung Chang, Min-Suk Song, Hye Won Jeong, Younho Choi, Weiqiang Chen, Woo-Jin Shin, Jae U. Jung, Young Ki Choi   +18 more
doaj   +1 more source

Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins

Cell Reports Medicine, 2021
Summary: After centuries of pestilence and decades of global vaccination, measles virus (MeV) genotypes capable of evading vaccine-induced immunity have not emerged. Here, by systematically building mutations into the hemagglutinin (H) glycoprotein of an
Miguel Ángel Muñoz-Alía, Rebecca A. Nace, Lianwen Zhang, Stephen J. Russell   +3 more
doaj   +1 more source

Investigation of the effect of mutual vaccination with pest des petits ruminants and polyvalent foot and mouth disease vaccines on the immune response of sheep

Open Veterinary Journal, 2023
Background: Pest des petits ruminants (PPR) and Foot and Mouth Disease (FMD) are two viral infectious diseases affecting sheep dramatically causing great economic losses.
Toka Yaser, Nabil Bkear, Yassien Badr, Ehab El-Sayed Ibrahim, Mohamed Hassan Khodeir   +4 more
doaj   +1 more source

Evaluation Of Anti-Rabies Hyperimmune Serum Prepared Using Different Adjuvants

Journal of Applied Veterinary Sciences, 2020
Anti-rabies virus hyperimmune serum was prepared in horses using both inactivated and live attenuated rabies virus (ERA strain) adjuvanted with three different adjuvants including 20% Alhydro gel, 5% Pet gel-A and 20% calcium phosphate gel.
Edries, S.M., Lamees, A, El – Tantawy, Wafaa, R, Abdel Aziz, Ibrahim, H.M., Omaima A.A. Al-Shamandy   +4 more
doaj   +1 more source

HoBi-like Pestivirus Is Highly Prevalent in Cattle Herds in the Amazon Region (Northern Brazil)

Viruses, 2023
Pestiviruses are globally distributed and cause substantial economic losses to the cattle industry. In Brazil, the country with the world’s largest cattle population, pestivirus infections are well described in some regions, such as in the south, where a
Leticia F. Baumbach, Ana Cristina S. Mósena, Raquel S. Alves, Laura J. Camargo, Juliana C. Olegário, Leonardo R. Lobraico, João Marcos N. Costa, Mauro R. Borba, Fernando V. Bauermann, Matheus N. Weber, Cláudio W. Canal   +10 more
doaj   +1 more source

Serotypes of bovine rotaviruses distinguished by serum neutralization [PDF]

Infection and Immunity, 1983
Fourteen cytopathic bovine rotaviruses isolated from naturally affected calves were characterized serologically by serum neutralization. Antisera were prepared in guinea pigs against the three isolates and the Lincoln strain of bovine rotavirus. These four rotaviruses were segregated into at least two distinct serotypes (designated types 1 and 2) by ...
Y, Murakami, N, Nishioka, Y, Hashiguchi, C, Kuniyasu   +3 more
openaire   +2 more sources

Ensaio imunoenzimático comercial no diagnóstico sorológico das infecções por herpesvírus bovino 1 A commercial enzyme immune assay in serodiagnosis of bovine herpesvirus 1 infections

Ciência Rural, 2000
Avaliou-se o desempenho de um ensaio imunoenzimático, obtido de fonte comercial, na identificação de anticorpos contra herpesvírus bovino tipo 1 (BHV-1), induzidos tanto por infecção natural quanto por vacinação, em 1000 amostras de soros sangüíneos de ...
Kerlei Cristina Médici, Amauri Alcindo Alfieri, Alice Fernandes Alfieri   +2 more
doaj   +1 more source

Saturation time of exposure interval for cross-neutralization response to SARS-CoV-2: Implications for vaccine dose interval

iScience, 2023
Summary: Evaluating the serum cross-neutralization responses after breakthrough infection with various SARS-CoV-2 variants provides valuable insight for developing variant-proof COVID-19 booster vaccines.
Sho Miyamoto, Yudai Kuroda, Takayuki Kanno, Akira Ueno, Nozomi Shiwa-Sudo, Naoko Iwata-Yoshikawa, Yusuke Sakai, Noriyo Nagata, Takeshi Arashiro, Akira Ainai, Saya Moriyama, Noriko Kishida, Shinji Watanabe, Kiyoko Nojima, Yohei Seki, Takuo Mizukami, Hideki Hasegawa, Hideki Ebihara, Shuetsu Fukushi, Yoshimasa Takahashi, Ken Maeda, Tadaki Suzuki   +21 more
doaj   +1 more source

Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals

Frontiers in Immunology, 2021
Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role in the development of vaccines and antibody-based interventions.
Savannah E. Butler, Andrew R. Crowley, Harini Natarajan, Shiwei Xu, Joshua A. Weiner, Carly A. Bobak, Daniel E. Mattox, Jiwon Lee, Wendy Wieland-Alter, Ruth I. Connor, Peter F. Wright, Margaret E. Ackerman, Margaret E. Ackerman, Margaret E. Ackerman   +13 more
doaj   +1 more source

Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay

Vaccines, 2021
This protocol describes an ELISA-based procedure for accurate measurement of SARS-CoV-2 spike protein-receptor binding domain (RBD) neutralization efficacy by murine immune serum.
Ahmed O. Shalash, Armira Azuar, Harrison Y. R. Madge, Naphak Modhiran, Alberto A. Amarilla, Benjamin Liang, Alexander A. Khromykh, Daniel Watterson, Paul R. Young, Istvan Toth, Mariusz Skwarczynski   +10 more
doaj   +1 more source