Results 81 to 90 of about 151,984 (257)
Advanced Science, EarlyView.Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
Association between body mass index and hemoglobin A1c with serum prostate-specific antigen level: A retrospective cohort study. [PDF]
Saudi Med J, 2023 Alhamdan WA +5 more
europepmc +1 more source
Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor
Advanced Science, EarlyView.The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao +11 more
wiley +1 more source
Serum prostate-specific antigen trends and prostate cancer detection on follow-up in men with a prior negative biopsy: A cohort study. [PDF]
Indian J Urol, 2023 Modi A, Singh P, Seth A, Kumar R.
europepmc +1 more source
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
Advanced Science, EarlyView.PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the frequency of prostate carcinoma having raised serum Prostate Specific Antigen level in Transurethral Resection of Prostate (TURP) specimens sent for histopathology. Study Design: Descriptive, cross sectional study. Place
Unaiza Jamil +5 more
doaj
Serum prostate specific antigen is a good indicator of prostatic volume in men with benign prostatic hyperplasia. [PDF]
Afr J Prim Health Care Fam Med, 2022 Abotsi E, Adanu KK, Bansah EC.
europepmc +1 more source
Advanced Science, EarlyView.Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan +11 more
wiley +1 more source
THE EFFECT OF EXERCİSE ON SERUM PROSTATE SPECİFİC ANTİGEN LEVELS
Urology Research and Practice, 2019 -
Y. Aksoy +4 more
doaj +2 more sources
Baghdad Journal of Biochemistry and Applied Biological Sciences, 2020 Background: Prostate cancer is one of the most common cancers in men, worldwide. Many markers are suggested for prostate cancer with different specificity and sensitivity.
Amal A. Hussein +2 more
doaj