Results 151 to 160 of about 1,640,389 (263)

Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery. [PDF]

Adv Drug Deliv Rev, 2023
Kim W, Ly NK, He Y, Li Y, Yuan Z, Yeo Y.
europepmc   +1 more source

Serum Protein [PDF]

, 2020
openaire   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A label-free microLC-SWATH-MS methodology with immunoaffinity depletion of highly abundant serum proteins for quantitative proteomic comparison of fresh-frozen human normal breast tissue and tumor clinical specimens. [PDF]

Front Mol Biosci
Macur K, Bogucka AE, Fel-Tukalska A, Skokowski J, Ołdziej S, Czaplewska P.   +5 more
europepmc   +1 more source

Targeted proteomic scan identifies alteration of serum proteins among workers occupationally exposed to low levels of trichloroethylene. [PDF]

Environ Mol Mutagen, 2022
Hosgood HD, Rahman ML, Blansky D, Hu W, Davitt M, Wen C, Huang Y, Tang X, Li L, Smith MT, Zhang L, Vermeulen R, Rothman N, Bassig BA, Lan Q.   +14 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Synergistic and individual actions of nanoemulsified vegetable oil and betaine as natural growth promoters on broiler performance, serum proteins, lipid profile, and safety enzymes. [PDF]

PLoS One
Al-Garadi MA, Suliman GM, Hussein EO, Al-Owaimer AN, Swelum AA, Almalamh NA, Alhotan RA, Qaid MM.   +7 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Serum proteins and faecal microbiota as potential biomarkers in newly diagnosed, treatment-naïve inflammatory bowel disease and irritable bowel syndrome patients. [PDF]

J Mol Med (Berl)
Matijašić M, Barešić A, Čipčić Paljetak H, Perić M, Panek M, Kunović A, Ljubas Kelečić D, Vranešić Bender D, Grubelić Ravić K, Rogić D, Antolic M, Horvat I, Kraljević I, Banić M, Krznarić Ž, Verbanac D.   +15 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source