Results 81 to 90 of about 4,061,589 (298)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Unraveling the Serum Protein Landscape in Celiac Disease: Current Evidence and Future Directions

open access: yesImmunity, Inflammation and Disease
Background Celiac disease (CD) is a chronic autoimmune disorder characterized by an abnormal immune response to gluten, leading to intestinal inflammation and various clinical manifestations.
Sajjad Bakhtiari   +6 more
doaj   +1 more source

Influência do fornecimento prolongado de colostro sobre a flutuação de proteínas séricas em bezerros com diferentes níveis de imunidade passiva sérica Influence of extended colostrum feeding on protein fluctuation of new born calves with different acquired passive immunity

open access: yesScientia Agricola, 1995
O presente trabalho teve como objetivo avaliar o comportamento das proteínas séricas de 32 bezerros recém-nascidos submetidos a diferentes programas de aleitamento.
R.S. Baracat   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The purification and characterisation of novel dipeptidyl peptidase IV-like activity from bovine serum [PDF]

open access: yes, 2004
The discovery of a potentially novel proline-specific peptidase from bovine serum is presented which is capable of cleaving the dipeptidyl peptidase IV (DPIV) substrate Gly-Pro-MCA.
Buckley, Seamus J.   +3 more
core   +2 more sources

Vivid Life Serum | Vivid Life Anti Aging Serum

open access: yes, 2021
Vivid Life Serum This concentrate will raise your degrees Vivid Life Anti Aging Serum hyaluronic corrosive by deinitiating a specific protein which is the reason for the acids breakdown.
Vivid Life Serum
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

IMPACT OF DIETARY PROBIOTIC SUPPLEMENTATION ON BEHAVIOR, GROWTH PERFORMANCE, AND SERUM PROTEIN PROFILES IN BROILER CHICKENS [PDF]

open access: yesAssiut Veterinary Medical Journal
The global withdrawal of antimicrobial growth promoters (AGPs) in poultry production has intensified the search for effective alternatives. This study investigated the effects of a Bacillus-based probiotic (Amnil®) on behavior, performance, and serum ...
ABEER ABDELATTY   +4 more
doaj   +1 more source

Serum Proteins [PDF]

open access: yesJournal of Clinical Pathology, 1949
J R, Marrack, H, Hoch
openaire   +2 more sources

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