Results 61 to 70 of about 1,253 (206)

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Serum Interleukin-41 Levels may have a Potential Clinical Value in Patients with Rheumatoid Arthritis. [PDF]

International Journal of Medical Arts
Background: One of the immunobiological factors thought to have modulatory effects in rheumatoid arthritis [RA] is interleukin-41 [IL-41], a recently identified cytokine claimed to be up-regulated in RA patients.The aim of the work: The objective of our ...
Sherif Kandeel, Mohamad Ali, Badawy Yossef   +2 more
doaj   +1 more source

Turbidimetry of rheumatoid factor in serum with a centrifugal analyzer.

Clinical Chemistry, 1986
Abstract We describe the simple, rapid turbidimetry of IgM rheumatoid factor in human serum by use of the Cobas-Bio centrifugal analyzer. Heat-aggregated human IgG is used as the antigen. The immunoturbidimetric reaction is monitored at 340 nm for 300 s, and the changes in absorbance after the antigen is added are used to prepare the ...
L, Borque, M, Yago, C, Mar, C, Rodriguez
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Neopterin as a Surrogate Marker for Coronary Artery Disease in Rheumatoid Arthritis

مجلة كلية الطب
Background: Rheumatoid arthritis is an inflammatory illness. A complication of Rheumatoid arthritis is mainly linked to the risk of cardiovascular disease.
Maryam K. Khaery, Rana A. Hamdi
doaj   +1 more source

The Role of Anti-TNFα Therapy in the Amelioration of Disease Burden in Patients with Refractory Rheumatoid Arthritis

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
To evaluate the changes in anti cyclic citrullinated peptide (Anti-CCP) antibodies, rheumatoid factor (RF), interleukins 17 and 10 (IL-17 and IL-10), high sensitivity C- reactive protein (hs CRP) and T regulatory cells (Treg) count following an anti TNF-
Madha Mohammed Sheet, Laith Abdul-Elah Kamel, Jamal Nasser Farhood   +2 more
doaj   +1 more source

Rheumatoid factors in the serum of gouty patients [PDF]

Arthritis & Rheumatism, 1977
F, Kozin, D J, McCarty
openaire   +2 more sources

Clinical study of rheumatoid factor (RF) in serum of rheumatoid arthritis (RA)

Orthopedics & Traumatology, 1983
Clinical data of 255 cases (1869 examinations) of definite or classical RA were analysed statistically and discussed on the correlation between with titers of RF (LATEX, RAHA and Waaler-Rose test) and with clinical findings.Titers of RF tend to increase in cases with high activities of general and joint symptoms in the following clinical data; general ...
Hirota, K., Ise, K., Tsukano, M.
openaire   +2 more sources

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source