Results 61 to 70 of about 41,493 (295)

Pathogenesis of Beta-lactam-induced Serum Sickness-Like Reaction: The potential role of Reactive Drug Metabolites

, 2020
Aims: Drug-induced serum sickness-like reactions (SSLRs) are idiosyncratic drug-induced hypersensitivity reactions that occur in susceptible patients 1-3 weeks after exposure to the culprit drug.
Abdelbaset A. Elzagallaai, Awatif M. Abuzgaia, Blanca Rosa Del Pozzo Magaña, E. Loubani, M. Rieder   +4 more
semanticscholar   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Clinical characteristics, diagnosis, treatment, and prognosis of rituximab-induced serum sickness: a retrospective analysis of 39 reported cases

Frontiers in Immunology
BackgroundRituximab-induced serum sickness (RISS) is an uncommon delayed hypersensitivity reaction with incompletely characterized clinical features and management.
Yi Huang, Wei Li, Yan Wang, Xiang Liu, Ying Huang   +4 more
doaj   +1 more source

Serum sickness‐like reaction associated with clopidogrel [PDF]

British Journal of Clinical Pharmacology, 2003
Clopidogrel (Plavix®) is a selective inhibitor of platelet aggregation used preventively in the setting of myocardial infarction, coronary stent implantation and stroke [1]. Clopidogrel structurally resembles another thienopyridine antiplatelet drug ticlopidine (Ticlid®) differing only by the presence of a carboxymethyl side group on clopidogrel.
Elizabeth J. Phillips, Sandra R. Knowles, Neil H. Shear   +2 more
openaire   +1 more source

Does treatment of acne with Retin A and tetracycline cause adverse effects? [PDF]

, 2004
Self-Adverse reactions to long-term tetracycline therapy are rare, and most will occur within 2 months of initiating therapy (strength of recommendation [SOR]: B, systematic review of ecological studies).
Burroughs, Martha, Kelly, Barbara F.
core  

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Systemic illness with eosinophilia and urticaria-like rash caused by prolonged bedbug exposure

International Journal of Infectious Diseases
Bedbugs are blood-feeding nocturnal ectoparasites, which are well-adapted to human habitats. In recent decades, bedbug infestation has been an emerging health problem worldwide, affecting all socio-economic population strata.
Ian B. Weitzel, Valeria Palma, Macarena Silva, Alex Castro, Thomas Weitzel   +4 more
doaj   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Molecular‐Level Insights into Interfacial Adsorption Mechanisms of PFOA on Functional Dolomite Surfaces via AIMD and Spectroscopy

Advanced Materials Interfaces, EarlyView.
Perfluorooctanoic acid (PFOA), ab initio molecular dynamics (AIMD), density functional theory (DFT), Dolomite (DL), metal‐organic frameworks (MOFs), calcined modified dolomite (CDL), zero‐point of charge (PZC), metal‐organic frameworks (MOFs), Fourier transform infrared (FTIR), X‐ray diffraction (XRD), scanning electron microscopy (SEM ...
Yating Yang, Yuhan Li, Zhaohui Li, Hang Wei, Yaqi Wen, Po‐Hsiang Chang, Christopher Rensing, Ahmed I. Osman, Baoyu Kong   +8 more
wiley   +1 more source