Results 91 to 100 of about 1,892,741 (310)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A systematic review and meta-analysis on serum and salivary levels of total antioxidant capacity and C-reactive protein in oral lichen planus patients

open access: yes, 2022
Objective: Oral lichen planus (OLP) is an inflammatory disease that total antioxidant capacity (TAC) and C-reactive protein (CRP) play an important role in its pathogenesis.
Mozaffari, HR   +5 more
core   +1 more source

Influence of Dietary Protein on Serum Total Protein and Albumin

open access: yesEiyo To Shokuryo, 1980
血清総たん白, アルブミンレベルに対する摂取たん白質の影響を検討した結果, つぎの点が明らかにされた。(1) 各種たん白質で飼育したラットの血清総たん白, アルブミンレベルはカゼイン群で最も高く, ついでツェイン群, カゼイン水解物群, ゼラチン群の順番となり, たん白質の種類によって明らかな差異がみられた。(2) 食餌中のたん白 (カゼイン) 含量を変えた場合には, 総たん白, アルブミンレベルともに無たん白食, 低たん白食では低いレベルを維持していたが, カゼイン含量の増加とともに上昇し, 25%含有食までほぼ直線的に上昇した。高たん白食でもその値は上昇していたが, 増加率においてやや劣る傾向を示した。(3) 低たん白 (2%カゼイン) 食で飼育したラットの飼育日数による変化を調べたところ ...
YOKOZAWA, Takako   +4 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Quantification of growth hormone in serum by isotope dilution mass spectrometry

open access: yes, 2009
Inter-assay variation of antibody based routine tests is hampering comparability of measurement results for growth hormone (GH) between different laboratories and decision making in clinical practice. Here it is demonstrated, that quantification of GH by
André Henrion   +4 more
core  

Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]

open access: yes, 2005
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Briegel, Josef   +4 more
core   +1 more source

Hubungan Malnutrisi Jumlah Total Albumin dan Protein Serum Terhadap Aktivitas Siswa

open access: yesJurnal Ilmiah Biosaintropis (Bioscience-Tropic)
Albumin dan Protein merupakan salah satu tolak ukur terhadap penentuan malnutrisi terhadap status gizi manusia. Keduanya dapat mengidentifikasi apakah ada korelasi terhadap aktivitas siswa yang rutin sarapan pagi dan yang tidak.
Ratno Budiyanto   +2 more
doaj   +1 more source

Standards for Total Serum Protein Assays— A Collaborative Study

open access: yesClinical Chemistry, 1975
Abstract We have studied the standardization of total serum protein assay with the biuret reaction. Standard solutions were prepared from lyophilized preparations of human serum albumin and bovine serum albumin, with corrections made for volatile material and ash contents.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease

open access: yes, 2014
Buruli ulcer is a skin disease caused by Mycobacterium ulcerans that is spreading in tropical countries, with major public health and economic implications in West Africa.
Reid Oldenburg (550232)   +63 more
core   +1 more source

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