Results 81 to 90 of about 1,892,741 (310)

Extraction and Purification of Scleroprotein Obtained from Spiderweb [PDF]

BIO Web of Conferences
Spider silk belonged to the scleroprotein family; a group of structural proteins found in living organisms. Other members of this group include collagen, present in ligaments, and keratin, which forms fingernails, feathers, horns, and hoofs.
Nithya M., Harunee R.V., Yeswandhini S., Nandhakumar V., Ajith N., Asothama Chakravarthi V.   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

HUBUNGAN ANTARA KADAR SENG (Zn) SERUM DENGAN SKOR TUBERKULOSIS PARU ANAK (The Association Between Serum Zinc (Zn) level and Pulmonary Tuberculosis Score in Children) [PDF]

, 2008
Tujuan : Mengetahui hubungan kadar seng (Zn) serum dengan skor tuberkulosis (TB) paru anak dan menilai hubungan faktor lain yang terkait dengan terjadinya TB paru anak ( status gizi, kadar Hemoglobin, kadar feritin ).
Pryjambodo, Medy
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population [PDF]

, 2000
Background: Increased values of C-reactive protein (CRP), the classical acute phase protein, within the range below 5 mg/L, previously considered to be within the reference interval, are strongly associated with increased risk of atherothrombotic events,
Hutchinson, W.L., Lowe, G.D.O., Koenig, W., Frohlich, M., Sund, M., Pepys, M.B.   +5 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

СЕЗОННА ДИНАМИКА НА ОБЩИЯ СЕРУМЕН ПРОТЕИН, УРЕЯ И АКТИВНОСТ НА АСПАРТАТ ТРАНСФЕРАЗАТА В КРЪВТА ПРИ КРАВИ С ОВАРИАЛНИ ЦИСТИ

Животновъдни науки, 2012
Higher intake of dietary protein has been negatively associated with metabolic changes in blood serum and reproductive performance in dairy cows. The aims of this study were to establish the incidence of cystic ovarian disease (COD), its seasonal ...
ГЕОРГИ БОНЕВ, СТАНИМИР ДИМИТРОВ, СВЕТЛАНА ГЕОРГИЕВА, ПЕТКАНА БАДАРОВА, ВЕСНА К. ХРИСТОВА, ИВАН КАБАДЖОВ   +5 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Comparison of Total Protein of Ascites Fluid with Serum Ascites Albumin Gradient as Criterion in the Differential Diagnosis of Ascites

پزشکی بالینی ابن سینا, 1999
A total 97 paired serum & ascites fluid samples from ascitic  patients  were           collected and  analyzed.      The   utility   of   the     serum - ascites   albumin  gradient  &   the   exudate     transudate concept as defined by ascitic fluid
Mostafa Ansari, Mehrdad Hajiloie
doaj   +2 more sources