Results 111 to 120 of about 1,718,808 (353)

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, Volume 599, Issue 8, Page 1094-1112, April 2025.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

Blind quantum computation with completely classical client and a trusted center [PDF]

open access: yesarXiv, 2015
Blind quantum computation (BQC) enables a client without enough quantum power to delegate his quantum computation to a quantum server, while keeping the input data, the algorithm and the result unknown to the server. In the studies of practical BQC protocol, an important problem is how to reduce the quantum requirement of the client.
arxiv  

Vienna RNA secondary structure server

open access: yesNucleic Acids Res., 2003
The Vienna RNA secondary structure server provides a web interface to the most frequently used functions of the Vienna RNA software package for the analysis of RNA secondary structures.
I. Hofacker
semanticscholar   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

WLAN Integrated with GPRS Network Securely

open access: yesAl-Khawarizmi Engineering Journal, 2012
In this paper a WLAN network that accesses the Internet through a GPRS network was implemented and tested. The proposed network is managed by the Linux based server.
Mohammed A. Abdalla   +2 more
doaj   +2 more sources

Human non-synonymous SNPs: server and survey.

open access: yesNucleic Acids Research, 2002
Human single nucleotide polymorphisms (SNPs) represent the most frequent type of human population DNA variation. One of the main goals of SNP research is to understand the genetics of the human phenotype variation and especially the genetic basis of ...
V. Ramensky, P. Bork, S. Sunyaev
semanticscholar   +1 more source

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

A Stochastic Reliability Model of a Server under a Random Workload [PDF]

open access: yesarXiv, 2015
Traffic to any server is rarely constant over time. In addition, the workload brought by each service request is typically unknown in advance, and each request may bring a different workload to the server. Cha and Lee (2011) proposed a reliability model where each request brings an identical and constant workload. In this paper, we generalize the model
arxiv  

Fatih Civarındaki Abideler [PDF]

open access: yes, 1963
Taha Toros Arşivi, Dosya No: 12-Fatih-Edirnekapıİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...
Revnakoğlu, Cemalettin Server
core  

Load Balancing via Random Local Search in Closed and Open systems

open access: yes, 2010
In this paper, we analyze the performance of random load resampling and migration strategies in parallel server systems. Clients initially attach to an arbitrary server, but may switch server independently at random instants of time in an attempt to ...
Ganesh, A.   +4 more
core   +2 more sources

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