Results 41 to 50 of about 3,072 (244)
N parallel queueing systems with server breakdown and repair [PDF]
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openaire +2 more sources
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
This paper deals with the steady state analysis of batch arrival retrial queueing system with two types of service under modified vacation policy, where each type consists of an optional re-service.
P. Rajadurai +2 more
doaj +1 more source
An Optimal Rejuvenation Strategy for Increasing Service Reliability of a VOIP System with Multiple Components [PDF]
In this day and age Voice over Internet Protocol (VoIP) has turned out to be a revolutionary technology in the field of telecommunication. Because of the escalating number of users of VoIP, it is essential to intend for a reliable VoIP system providing ...
Vandana Gupta, Rahul Kumar
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Alkaptonuria (AKU), a rare genetic disorder, is characterized by the accumulation of homogentisic acid (HGA) in the body. Affected individuals lack functional levels of an enzyme required to breakdown HGA.
Malancha Karmakar +5 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The well-posedness of an M/G/1 queue with second optional service and server breakdown
In this paper, the solution of an M/G/1 queue with second optional service and server breakdown is investigated. By using the method of functional analysis, especially, the linear operator theory and the C0 semigroup theory on Banach space, we prove the ...
Wang, Wen-Long, Xu, Gen-Qi
core +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source

