Results 41 to 50 of about 2,185,055 (279)

Analysis of an M[X]/(G1,G2)/1 retrial queueing system with balking, optional re-service under modified vacation policy and service interruption

Ain Shams Engineering Journal, 2014
This paper deals with the steady state analysis of batch arrival retrial queueing system with two types of service under modified vacation policy, where each type consists of an optional re-service.
P. Rajadurai, M.C. Saravanarajan, V.M. Chandrasekaran   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Influence of low amounts of nanostructured silica and calcium carbonate fillers on the large-area dielectric breakdown performance of bi-axially oriented polypropylene [PDF]

, 2014
Influence of low amounts (1.0-2.0wt-%) of nanostructured silica and calcium carbonate fillers on the large area dielectric breakdown performance of bi-axially oriented polypropylene (BOPP) is analyzed.
S. Virtanen, K. Lahti, I. Rytoluoto, Virtanen, Suvi, M. Pettersson, Karttunen, Mikko, Lahti, Kari, M. Koponen, M. Karttunen, Rytöluoto, Ilkka, Rytöluoto, Ilkka; id_orcid, Koponen, M., Pettersson, Mika, Koponen, Matti   +13 more
core   +2 more sources

Analysis of a Discrete-Time Queueing Model with Disasters

Mathematics, 2021
Queueing models with disasters can be used to evaluate the impact of a breakdown or a system reset in a service facility. In this paper, we consider a discrete-time single-server queueing system with general independent arrivals and general independent ...
Mustafa Demircioglu, Herwig Bruneel, Sabine Wittevrongel   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

An Optimal Rejuvenation Strategy for Increasing Service Reliability of a VOIP System with Multiple Components [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2017
In this day and age Voice over Internet Protocol (VoIP) has turned out to be a revolutionary technology in the field of telecommunication. Because of the escalating number of users of VoIP, it is essential to intend for a reliable VoIP system providing ...
Vandana Gupta, Rahul Kumar
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Multi-Server Two-Way Communication Retrial Queue Subject to Disaster and Synchronous Working Vacation

Algorithms
This research analyzes a multi-server retrial queue with two types of calls: working vacation and working breakdown. The incoming call may enter the retrial queue and attempt to seize a server after a random delay if all the servers are unavailable upon ...
Tzu-Hsin Liu, He-Yao Hsu, Fu-Min Chang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source