Results 61 to 70 of about 6,920,344 (259)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Minnesota Feed Service 1963:Fall
, 1963 University of Minnesota, Agricultural Extension Service; Rust, J.W.; Bowland, J.P.; Waibel, P.E.; Egertson, K; Hasbargen, P.. (1963). Minnesota Feed Service 1963:Fall.
Rust, J.W. +5 more
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, 1930 This document summarizes various statistics about Alabama agriculture and farm life for 1930 to demonstrate the value to Alabama of the Extension Service.
Alabama Polytechnic Institute. Extension Service
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Oregon Outdoor School : strengthening student success in and out of school
Biennial report 2022-2024. Low- and high-resolution versions available for download.Every year, a growing number of fifth and sixth graders across Oregon get to be part of a transformative, multi-day experience in the world’s greatest classroom.
Oregon State University. Extension Service
core +5 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Health Service Executive national service plan 2014 [PDF]
, 2013 This National Service Plan 2014 (NSP2014) is the first annual plan presented by the Directorate of the Health Service (hereafter in this Plan referred to as the Health Service), following the enactment of the Health Service Executive1 (Governance) Act ...
Health Service Executive (HSE)
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
, 2013 The Federal Power Act authorizes the Service to condition a non-Federal hydropower license with fish passage facilities and, if the project is in Service managed land (e.g., utilizes part of a hatchery water intake system), to require measures that ...
U.S. Fish and Wildlife Service
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Aktuelle Veröffentlichungen zum Themenfeld „Hochschule und Weiterbildung”
Zeitschrift Hochschule und Weiterbildung, 2021 Ein Service der Bibliothek des DIE
doaj +1 more source