Results 71 to 80 of about 11,863,905 (304)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
McMinnville Habitat for Humanity: Homeownership and Resources Survey [PDF]
This report outlines the overall satisfaction that homeowners feel in regards to their new homes provided through the Habitat for Humanity program. Details include the overall building experience for Habitat for Humanity homeowners, and the report also ...
Peterson, Jeff D.
core +1 more source
Personal and Professional Readiness of Public Servants
In the article the system of formation of personal and professional readiness of public servants in modern conditions is considered. The author based on differentiation between objects of management in public administration and management postulates ...
Victor Leonidovich Cheplyaev
doaj
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
If you haven’t noticed yet, we’ve had some really spectacular visitors from the south with us on Gettysburg’s campus the last few days! The Random Acts of Theater Company (RATCo) is a group that emerged from the Freedom Foundation in Denver, Colorado a ...
Center for Public Service,
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Resource allocation improvement in the tasks of airport ground handling operations
It is a global trend for the airport ground handling market to become liberalised. Fiercer competition lead to the necessity to improve efficiency and minimise costs. A mathematical model of optimal resource allocation by aircraft ground handling company
Kristina Marintseva +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Lady Gaga, Racist Jokes, and Other Pet Peeves
When I was a kid, my sister would whistle whenever I entered a room because she knew that it bothered me. I picked up on this trick, and I use it even now that I’m older.
Center for Public Service,
core
Legal Classification of Employment Relations of State Bureau of Investigation Personnel
The sectoral affiliation of employment relations concerning personnel of the State Bureau of Investigation (SBI) is examined. The scholarly contributions regarding the classification of service relations within law enforcement agencies are analyzed ...
D. Ye. Zherebtsov
doaj +1 more source

