Results 61 to 70 of about 463,297 (313)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Health indicators for remote service delivery communities [PDF]
, 2014 Provides information on antenatal care, live births, low birthweight babies, hospitalisations (all and selected causes), disability, mortality, child protection, juvenile justice, alcohol and other drug use and aged care for 29 remote Indigenous ...
core
Journal of Engineering and Applied ScienceEfficient composition of cloud services under Quality of Service (QoS) constraints is a critical challenge in service-oriented computing. Traditional metaheuristic approaches often struggle to balance global exploration and SLA compliance in high ...
Dongge Tian
doaj +1 more source
SLA-Based Service Provisioning Optimization in Vehicular Cloud Networks Using Fuzzy Logic
IEEE AccessVehicular Cloud Networks (VCNs) enable vehicles to act as servers and share their abundant computing and storage resources. However, resource allocation in VCNs faces challenges due to factors like service pricing, resource variability, and mobility ...
Farhoud Jafari Kaleibar, Marc St-Hilaire
doaj +1 more source
Service Level Agreements: Web Services and Security [PDF]
, 2007 To support the quality of service guarantee from the service provider side, complex web services require to be contracted through service level agreement. State of the art on web services and web service compositions provides for a number of models for describing quality of service for web services and their compositions, languages for specifying ...
openaire +3 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Supporting service quality assurance via trouble management [PDF]
, 2000 The open service market encourages competition between service providers. To attract and keep customers, service providers require – amongst other things - better tools and techniques to increase their competitiveness.
Vortisch, W. +7 more
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Poredbeno Pomorsko Pravo, 2011 After fi nishing the process of liberalisation of air transport, the European Union has realised what benefi ts its air transport sector, carriers and economy could have if it would only spread its common aviation rules outside the borders of the EU.
Iva Savić, Ana Kapetanović
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source