Results 81 to 90 of about 4,707,888 (270)
Threats Management Throughout the Software Service Life-Cycle
, 2014 Software services are inevitably exposed to a fluctuating threat picture. Unfortunately, not all threats can be handled only with preventive measures during design and development, but also require adaptive mitigations at runtime.
Gjære, Erlend Andreas +1 more
core +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
ProceedingsService design is an emerging transdisciplinary research field that has received an increased interest in the last years. It has been used to improve service delivery, develop new and innovative services and provide value-added solutions in all the major
Ilias Tsotsas, Garyfallos Fragidis
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Improving Internal Communication Management in SMEs: Two Case Studies in Service Design
Technology Innovation Management Review, 2017 Effective information management is a success factor for business growth, but small and medium-sized enterprises (SMEs) face challenges in transferring knowledge and information from one organizational unit to another. In this study of two case companies,
Tuomo Eskelinen +3 more
doaj
Cocreando la experiencia de parir para mejorar la salud mental de las madres
Musas, 2023 Obstetric Coevolution is a service design approach to childbirth to reimagine the birthing experience. Service design consists of planning and structuring the role of people, infrastructure, communication and all the materials that make up a service, in ...
Irene Lapuente Aguilar
doaj
Exploring the UK high street retail experience: is the service encounter still valued? [PDF]
, 2014 Purpose: The relationship between service quality, the service encounter and the retail experience is explored within a changing UK retail environment. Design: Data was gathered from forty customers and twenty staff of an established UK health and ...
Foster, C, Resnick, S, Woodall, T
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
DIAGNOSTIC COMPLEX FOR IDENTIFING FAULTS OF MODERN CARS ENGINES
Вестник СибАДИ, 2017 Diagnostic practice shows that every year in order to improve environmental safety becomes more complicated engine design and its systems, and in particular the electronic control systems.
G. G. Musayelyants +2 more
doaj +1 more source