Results 71 to 80 of about 14,427,587 (243)

Need for Service Design Development for Sustainable Rural Tourism in Azerbaijan

Baltic Journal of European studies, 2014
‘Development of Sustainable Entrepreneurship and Support of Local Handicrafts in Rural Azerbaijan’ is a joint effort between the Turku University of Applied Sciences Ltd. and Sustainable Future in Finland and Ekoloji Tarazliq NGO as a local partner, with
Heikkilä Jonna, Poladova Aytan, Kääriä Juha   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Guided Forest Bathing as a Wellness Resort Experience: Immediate Outcomes, Guest Heterogeneity, and Implications for Service Design

Tourism and Hospitality
Guided forest bathing is increasingly incorporated into resort wellness portfolios, yet tourism evaluations often report average programme outcomes without examining how guests differ at entry or what the findings imply for product and service design ...
Aleksandar Racz, Ljerka Armano
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Service Systems Design for Full Lifecycle Sustainability of Distributed Photovoltaics in Urban and Rural Contexts

Systems
Distributed photovoltaics (DPV) is rapidly expanding under the “Dual Carbon” strategy, yet suffers from a systemic imbalance of prioritizing construction over service provision.
Yexin Chen, Xinyu Liu, Zhi Wang, Yuxin Xie, Xinyi Shen, Jiayi Zhao, Ziqin Wang, Chen Su   +7 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Combining machine learning and Service Design to improve customer experience

, 2021
Service design is an effective approach for service-based businesses to improve customer experience. However, Double Diamond design process has limitations in identifying the development areas with most business impact.
Falay von Flittner, Zeynep, Roto, Virpi, Vaajakallio, Kirsikka, Reunanen, Niko   +3 more
core   +1 more source

Driving lessons in service design

, 2011
This article provides five lessons for successful implementation of service design within the voluntary and community sector drawn from case-study work undertaken with Age ...
Bailey, Mark, Warwick, Laura
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

AI-powered service prototyping in service design agencies [PDF]

LAUREA MAGISTRALEQuesta tesi studia come l’IA stia cambiando il processo di prototipazione dei servizi nelle agenzie di service design. L’intelligenza artificiale (AI) promette di automatizzare i processi aziendali, compresa la prototipazione.
Alfansi, Annis Zarina
core