Results 31 to 40 of about 208,734 (256)

Scalable Architecture for Service Function Chain Orchestration [PDF]

2015 Fourth European Workshop on Software Defined Networks, 2015
Network Function Virtualization (NFV) enables to implement network functions in software, high-speed packet processing functions which traditionally are dominated by hardware implementations. Virtualized Network Functions (NFs) may be deployed on generic-purpose servers, e.g., in datacenters.
Sahel Sahhaf, Wouter Tavernier, János Czentye, Balázs Sonkoly, Pontus Sköldström, Dávid Jocha, Jokin Garay   +6 more
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Service function chain construct algorithm based on reliability

Tongxin xuebao, 2019
With the continuous expansion of network size and content quantity,network operators often face the problem of data transmission interruption,thus how to improve the reliability of data transmission has become a research hotspot.Started with the huge ...
Julong LAN, Zijin JIN, Penghao SUN, Yiming JIANG, Yue WANG   +4 more
doaj   +2 more sources

Security-aware Service Function Chain Deployment Method Based on Deep ReinforcementLearning [PDF]

Jisuanji kexue
As a key technology to improve the utilization of network resources,service function chain combined with deep reinforcement learning makes it possible to achieve flexible and secure deployment.However,how to effectively deploy service function chains ...
ZHU Ziyi, ZHANG Jianhui, ZENG Junjieand ZHANG Hongyuan
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Service function chain deployment algorithm based on optimal weighted graph matching

Tongxin xuebao, 2019
Service function chain can support flexible network service requirement by linking virtual network functions.Aiming at the problem of service function chain deployment in a resource-constrained network,an algorithm for service function chain deployment ...
Dan LI, Julong LAN, Peng WANG, Yuxiang HU   +3 more
doaj   +2 more sources