Results 51 to 60 of about 208,734 (256)

OpenRASE: Service Function Chain Emulation

2025 International Conference on Software, Telecommunications and Computer Networks (SoftCOM)
Service Function Chains (SFCs) are one of the key enablers in providing programmable computer networks, paving the way for network autonomy. However, this also introduces new challenges, such as resource allocation and optimisation related to their operation, requiring new algorithms to address these challenges.
Theviyanthan Krishnamohan, Paul Harvey 0002   +1 more
openaire   +4 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Attack Graph-assisted Deep Reinforcement Learning-based Service Function Chain AttackRecovery Method [PDF]

Jisuanji kexue
SFC can provide customized services for the six scenarios of 6G with the advantages of on-demand orchestration,flexible networking,and other benefits,and 6G networks also put forward higher requirements for SFC.Resilience is receiving attention for the ...
ZHOU Deqiang, JI Xinsheng, YOU Wei, QIU Hang , YANG Jie
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

ParaGraph: Subgraph-Level Network Function Composition With Delay Balanced Parallelism

IEEE Access, 2020
Recent efforts in the network function virtualization (NFV) field have targeted ameliorating end-to-end latency of service function chains (SFCs) using network function (NF) composition.
Dian Shen, Haoyang Liu, Rui Wang, Fang Dong, Fucun Li   +4 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Availability and Reliability of Service Function Chain: A Quantitative Evaluation View

International Journal of Computational Intelligence Systems, 2023
Service function chain (SFC) based on network function virtualization (NFV) technology can handle network traffic flexibly and efficiently. The virtual network function (VNF), as the core function unit of SFC, can experience software aging, which reduces
Yaru Li, Lin Li, Jing Bai, Xiaolin Chang, Yingying Yao, Peide Liu   +5 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A satellite SFCs reliability protection method [PDF]

Zhihui kongzhi yu fangzhen
This paper discusses the reliability deployment of Service Function Chain (SFC) on the hybrid satellite network based on SDN architecture. Firstly, this paper describes the reliability protection problem of SFC, establishes the underlying network and SFC
WANG Zhong, WU Yang, SONG Huayu, LI Feilong
doaj   +1 more source

Optimal Service Function Chain Composition in Network Functions Virtualization [PDF]

, 2017
AbstractNetwork Functions Virtualization (NFV) is an emerging initiative where virtualization is used to consolidate Network Functions (NFs) onto high volume servers (HVS), switches, and storage. In addition, NFV provides flexibility as Virtual Network Functions (VNFs) can be moved to different locations in the network.
Andrés F. Ocampo, Juliver Gil-Herrera, Pedro Heleno Isolani, Miguel Neves, Juan Felipe Botero, Steven Latré, L Zambenedetti, Marinho Barcellos, Luciano Paschoal Gaspary   +8 more
openaire   +3 more sources