Results 61 to 70 of about 191,071 (260)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
IEEE Access, 2019 In this paper, in order to improve network security, we propose an optimal placement of security virtual network function (security VNF) for service function chains based on the security level.
Dhanu Dwiardhika, Takuji Tachibana
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
On disaster-resilient hybrid service function chains
IEEE INFOCOM 2025 - IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS)Network Function Virtualization (NFV), offers a flexible solution through the orchestration of Virtual Network Functions (VNFs) into a Service Function Chain (SFC), facilitating the seamless transfer of user data between customers and edge servers/clouds. The distinct requirements of forward and backward traffic necessitate a Hybrid SFC (HSFC) approach.
Madani, Mohamed +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
SFP selection algorithm for SFC
Dianxin kexue, 2017 In order to achieve the new business deployment model by the convergence of cloud and network,SFC technology has been promoted greatly.As one of the key technologies in SFC,the SFP selection strategy affects the network performance and business ...
Yongqing ZHU, Xia GONG, Huanan CHEN
doaj +2 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Service function chain deployment scheme based on heterogeneous backup and remapping
网络与信息安全学报, 2018 Network function virtualization technology improves the flexibility of service function chains' deployment.However,the virtual network functions are under the pressure of uncertain failures and malicious attacks.The existing redundant backup methods can ...
Jichao XIE +4 more
doaj +3 more sources